{"id":"W2135498571","doi":"10.1128/jvi.02434-09","title":"Adenovirus Protein E4orf4 Induces Premature APC <sup>Cdc20</sup> Activation in <i>Saccharomyces cerevisiae</i> by a Protein Phosphatase 2A-Dependent Mechanism","year":2010,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre","funders":"Canadian Institutes of Health Research","keywords":"Protein phosphatase 2; Biology; Saccharomyces cerevisiae; CDC20; Mitosis; Cyclin-dependent kinase 1; Phosphatase; Protein subunit; Cell biology; Cell Cycle Protein; Cell cycle; Molecular biology; Yeast; Genetics; Anaphase; Cell; Phosphorylation; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001286402,0.0003785623,0.0001731194,0.0001749943,0.0001196236,0.0002657679,0.0001579211,0.0001813238,0.0008728781],"category_scores_gemma":[0.0001159887,0.0001384701,0.0003168671,0.0001151914,0.0001804943,0.00009460974,0.0001788075,0.0003204623,0.0002810725],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004692153,"about_ca_system_score_gemma":0.0001883754,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001277637,"about_ca_topic_score_gemma":0.001153423,"domain_scores_codex":[0.9998786,0.00002396575,0.00002155027,0.00001953712,0.00002432791,0.0000319073],"domain_scores_gemma":[0.9998689,0.00002984121,0.00003688814,0.00002425562,0.00001322713,0.00002695549],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009038154,0.00002069733,0.0002421734,0.0000167388,0.000005561714,0.00006247425,0.00000617651,0.00006119336,0.9989282,0.00007257327,0.00002955652,0.0004641608],"study_design_scores_gemma":[0.000006279493,0.0001524205,0.002193348,0.000001941952,0.000008433236,0.0001199678,0.00001316357,0.0007245032,0.9959025,0.00002577963,0.0008494476,0.000002230189],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973416,0.0003979488,0.001207343,0.00003011364,0.00002273906,0.00001486944,0.0003499762,0.0000632719,0.0005720898],"genre_scores_gemma":[0.9951612,0.0003032314,0.001281707,0.00003025244,0.00000536531,0.00001704099,0.001091713,0.00002605701,0.002083589],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001277637,"threshold_uncertainty_score":0.003404438,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004695309664723063,"score_gpt":0.2218503046167296,"score_spread":0.2171549949520065,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}