{"id":"W2135551310","doi":"10.1177/0300985810382672","title":"Experimental Transmission of H-Type Bovine Spongiform Encephalopathy to Bovinized Transgenic Mice","year":2010,"lang":"en","type":"article","venue":"Veterinary Pathology","topic":"Prion Diseases and Protein Misfolding","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Food Inspection Agency","funders":"","keywords":"Western blot; Bovine spongiform encephalopathy; Hippocampus; Biology; Medulla oblongata; Pathology; Cerebral cortex; Cerebellum; Immunohistochemistry; Thalamus; Globus pallidus; Genetically modified mouse; Molecular biology; Nucleus; Transgene; Endocrinology; Central nervous system; Prion protein; Cell biology; Basal ganglia; Immunology; Medicine; Biochemistry; Neuroscience","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001744056,0.0001641442,0.0001906702,0.00007019693,0.00005670716,0.000006232878,0.0002561715,0.0001814226,0.0002907683],"category_scores_gemma":[0.00003168593,0.0001589959,0.0001215661,0.0001089681,0.00007891617,0.000005399723,0.00009177646,0.0001090542,0.00001710801],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003403002,"about_ca_system_score_gemma":0.00005567991,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005669357,"about_ca_topic_score_gemma":0.000001511416,"domain_scores_codex":[0.9989934,0.00006889932,0.0002416263,0.0003573861,0.0000888717,0.0002498108],"domain_scores_gemma":[0.9994001,0.000009741561,0.00005671585,0.0003271923,0.00004754229,0.0001587081],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001793168,0.0001233625,0.0002058332,0.00002168005,0.00001065198,0.00003864084,0.000156347,0.000002872357,0.9829066,0.00002078847,0.00005719002,0.0146629],"study_design_scores_gemma":[0.0007345051,0.00496691,0.002084909,0.00001235581,0.00001257686,0.000306637,0.00005369455,0.00001450882,0.9304626,0.00001667475,0.06112539,0.0002092317],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996133,0.001673829,0.001181893,0.00007344703,0.0004385529,0.0002416608,0.00002775469,0.00001709812,0.0002127545],"genre_scores_gemma":[0.9940187,0.0001802831,0.005248372,0.0002046065,0.0001522467,0.00002699839,0.00005746232,0.00002419518,0.00008710468],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0610682,"threshold_uncertainty_score":0.6483666,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0146025644241792,"score_gpt":0.2864203264267793,"score_spread":0.2718177620026001,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}