{"id":"W2135551310","doi":"10.1177/0300985810382672","title":"Experimental Transmission of H-Type Bovine Spongiform Encephalopathy to Bovinized Transgenic Mice","year":2010,"lang":"en","type":"article","venue":"Veterinary Pathology","topic":"Prion Diseases and Protein Misfolding","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Food Inspection Agency","funders":"","keywords":"Western blot; Bovine spongiform encephalopathy; Hippocampus; Biology; Medulla oblongata; Pathology; Cerebral cortex; Cerebellum; Immunohistochemistry; Thalamus; Globus pallidus; Genetically modified mouse; Molecular biology; Nucleus; Transgene; Endocrinology; Central nervous system; Prion protein; Cell biology; Basal ganglia; Immunology; Medicine; Biochemistry; Neuroscience","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001157555,0.001621943,0.0005868554,0.001458905,0.0009424741,0.0005934035,0.0009323135,0.001344678,0.002567432],"category_scores_gemma":[0.0005324942,0.000588071,0.00058703,0.0005615764,0.001000252,0.00058109,0.0005515442,0.002142332,0.0005705471],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001711097,"about_ca_system_score_gemma":0.0009939048,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.008746864,"about_ca_topic_score_gemma":0.01343947,"domain_scores_codex":[0.9987769,0.0002073002,0.000118724,0.0003301029,0.000237965,0.0003290133],"domain_scores_gemma":[0.998871,0.000211957,0.0002829377,0.0001499497,0.0001000176,0.0003840477],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001388679,0.00141829,0.0009662821,0.00007925292,0.00004448476,0.0003893677,0.000227319,0.0001818968,0.9929593,0.0005371393,0.0002484163,0.001559586],"study_design_scores_gemma":[0.0010315,0.01381173,0.0206682,0.00009332514,0.0002201482,0.002672175,0.0002819382,0.003196568,0.948612,0.0005376297,0.008800942,0.0000737381],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9905393,0.0008577092,0.003175451,0.0002815042,0.00008677041,0.0005971007,0.001927618,0.0003019912,0.002232402],"genre_scores_gemma":[0.9674526,0.001903766,0.01095005,0.0004960227,0.0000873707,0.0009485112,0.004856984,0.000190307,0.01311436],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008746864,"threshold_uncertainty_score":0.01739192,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0146025644241792,"score_gpt":0.2864203264267793,"score_spread":0.2718177620026001,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}