{"id":"W2135635187","doi":"10.1194/jlr.m800013-jlr200","title":"Glucocorticoids and cyclic AMP selectively increase hepatic lipin-1 expression, and insulin acts antagonistically","year":2008,"lang":"en","type":"article","venue":"Journal of Lipid Research","topic":"Lipid metabolism and biosynthesis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":77,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Institutes of Health Research; University of Ottawa; University of Alberta","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health; National Human Genome Research Institute; Fondation pour la Recherche Médicale; Heart and Stroke Foundation of Canada","keywords":"Internal medicine; Endocrinology; Insulin; Chemistry; Cell biology; Biology; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008721618,0.0005090605,0.0002365827,0.0003511476,0.0001346879,0.0003299158,0.0001604609,0.000256487,0.002211108],"category_scores_gemma":[0.000140474,0.0001502704,0.0002355824,0.0002304981,0.0003775987,0.0001772962,0.0002263057,0.0004735556,0.0003298834],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000512006,"about_ca_system_score_gemma":0.0002638909,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006705457,"about_ca_topic_score_gemma":0.001691964,"domain_scores_codex":[0.9997858,0.00003803265,0.00001478266,0.00006771943,0.00004587788,0.00004774072],"domain_scores_gemma":[0.9997939,0.00003036969,0.00005472282,0.00002488425,0.00001658893,0.00007955224],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005403081,0.0000276084,0.0005205842,0.0000750575,0.00001194961,0.0001071653,0.00001604681,0.00003314032,0.9938984,0.0001645167,0.0001113863,0.004493855],"study_design_scores_gemma":[0.00007816861,0.00073338,0.02275949,0.0000245114,0.00005511289,0.0006981977,0.0001052734,0.0003038917,0.9633546,0.0002616332,0.01160872,0.0000169503],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9597094,0.02558277,0.004056737,0.0007705228,0.0004040852,0.00007355693,0.001308482,0.0002946905,0.007799706],"genre_scores_gemma":[0.9883916,0.004521946,0.002219426,0.0002738192,0.00009505438,0.00007202966,0.0007340382,0.00002777234,0.003664315],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002211108,"threshold_uncertainty_score":0.007396817,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03651593607715663,"score_gpt":0.3192649706444526,"score_spread":0.282749034567296,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}