{"id":"W2135671488","doi":"10.1016/s1470-2045(11)70287-x","title":"Cross-protective efficacy of HPV-16/18 AS04-adjuvanted vaccine against cervical infection and precancer caused by non-vaccine oncogenic HPV types: 4-year end-of-study analysis of the randomised, double-blind PATRICIA trial","year":2011,"lang":"en","type":"article","venue":"The Lancet Oncology","topic":"Cervical Cancer and HPV Research","field":"Medicine","cited_by":507,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba; University of Alberta","funders":"GlaxoSmithKline","keywords":"Medicine; Vaccine efficacy; Cohort; Serostatus; Cervical cancer; Vaccine trial; Vaccination; Adjuvant; HPV infection; Internal medicine; Oncology; Immunology; Cancer; Virus; Viral load","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001810161,0.000232778,0.00179037,0.0002845756,0.0001083669,0.000008528628,0.0003379852,0.0002536067,0.004997227],"category_scores_gemma":[0.0004193484,0.0001323542,0.0003614054,0.001722517,0.0002343705,0.00004977038,0.0002275181,0.0006231528,0.000003977731],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002457122,"about_ca_system_score_gemma":0.000389322,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004310604,"about_ca_topic_score_gemma":0.003609761,"domain_scores_codex":[0.9972864,0.0006130697,0.000865226,0.0004032422,0.000453825,0.00037828],"domain_scores_gemma":[0.9973172,0.0007138374,0.0005600356,0.0007318727,0.0005615862,0.000115464],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.8539444,0.002252528,0.1025511,0.0001778675,0.003856584,0.000004405522,0.002489257,0.00004738523,0.001899643,0.00001468792,0.0003190253,0.03244313],"study_design_scores_gemma":[0.389295,0.00368295,0.5981331,0.000008869065,0.002412392,0.000001627365,0.0001241629,0.0001919589,0.005760821,0.00002708358,0.0002669215,0.00009503824],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9864049,0.0004136091,0.00007595144,0.0002409382,0.0002077027,0.004022305,0.0000622052,0.00002028716,0.008552121],"genre_scores_gemma":[0.9986631,0.0004187592,0.00001694743,0.0001034839,0.0004074949,0.0002186867,0.00003075502,0.00002495775,0.0001157703],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4955821,"threshold_uncertainty_score":0.9959123,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09181201552947253,"score_gpt":0.4050317562153602,"score_spread":0.3132197406858876,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}