{"id":"W2135701553","doi":"10.1139/o07-143","title":"PAK: an essential motif for forming β-turn structures and exhibiting the thrombolytic effect of P6A and its analogs","year":2007,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Protein Kinase Regulation and GTPase Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"National Key Research and Development Program of China; Peking University; Memorial University of Newfoundland; National Natural Science Foundation of China","keywords":"Turn (biochemistry); Motif (music); Chemistry; Stereochemistry; Combinatorial chemistry; Biology; Biochemistry; Physics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009788141,0.0002949847,0.0001689861,0.0001062266,0.0001385095,0.0001927451,0.0001434846,0.00018746,0.0008667743],"category_scores_gemma":[0.0001572828,0.0001142221,0.0001780844,0.0001184584,0.0001968719,0.0002110357,0.0001225882,0.0004927377,0.0004943195],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000131106,"about_ca_system_score_gemma":0.0001328894,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001076329,"about_ca_topic_score_gemma":0.0001079125,"domain_scores_codex":[0.9999487,0.00001479819,0.00000495732,0.000009314498,0.00001109503,0.000011093],"domain_scores_gemma":[0.9998993,0.0000135707,0.00003571784,0.00001008072,0.000009830944,0.00003150586],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003880108,0.00005630213,0.0002746171,0.0000594677,0.000008830059,0.0002204072,0.00001925116,0.0006236564,0.9948165,0.000352893,0.00005849021,0.003121621],"study_design_scores_gemma":[0.00004816419,0.0009898433,0.001189323,0.000004815733,0.00001595066,0.001204303,0.00001248309,0.0008812168,0.9921826,0.0001413525,0.003323816,0.000006146759],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9919571,0.001089257,0.004935134,0.00009248039,0.00001598787,0.00004028327,0.0003086039,0.00005392466,0.001507338],"genre_scores_gemma":[0.9918172,0.000633802,0.006046275,0.00002961266,0.00001048765,0.00002232617,0.0005419562,0.00001900803,0.0008792548],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008667743,"threshold_uncertainty_score":0.002899647,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006616705813491159,"score_gpt":0.2588052760043681,"score_spread":0.252188570190877,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}