{"id":"W2135740919","doi":"10.1101/gr.073676.107","title":"The amphioxus genome illuminates vertebrate origins and cephalochordate biology","year":2008,"lang":"en","type":"article","venue":"Genome Research","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":511,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria; University of Toronto; Sunnybrook Health Science Centre","funders":"Biotechnology and Biological Sciences Research Council; Centre National de la Recherche Scientifique; Ministero dell’Istruzione, dell’Università e della Ricerca; National Institute of Allergy and Infectious Diseases; European Commission; Wellcome Trust; Japan Society for the Promotion of Science; Ministry of Education, Culture, Sports, Science and Technology; National Institutes of Health; National Science Foundation","keywords":"Chordate; Biology; Hox gene; Genome; Homeobox; Vertebrate; Genetics; Evolutionary biology; Gene; Enhancer; Gene duplication; Transcription factor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002705434,0.0004203073,0.0003017529,0.001146482,0.0004449488,0.000551976,0.0001997122,0.0003574094,0.002640131],"category_scores_gemma":[0.0003778477,0.0002070803,0.0003824208,0.001285824,0.000148129,0.0004842966,0.0005810764,0.0005989076,0.0005942564],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002358858,"about_ca_system_score_gemma":0.0004010809,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001806367,"about_ca_topic_score_gemma":0.003207085,"domain_scores_codex":[0.9998831,0.00001334211,0.000007084226,0.00005524121,0.0000268827,0.00001435694],"domain_scores_gemma":[0.9997947,0.00004560991,0.00003995413,0.00002474287,0.00005378339,0.00004135266],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0004450923,0.00007605785,0.07488003,0.002428191,0.0002888484,0.000906712,0.001096961,0.001159135,0.6918513,0.006348069,0.02180318,0.1987164],"study_design_scores_gemma":[0.00008804889,0.0001906928,0.5967587,0.0005312288,0.0004881161,0.001391314,0.0006005973,0.002866689,0.04432055,0.004458532,0.3482391,0.0000664247],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.777664,0.04789598,0.02037837,0.002541475,0.0005437194,0.0001032213,0.116546,0.001565302,0.03276198],"genre_scores_gemma":[0.8082286,0.02242574,0.04174753,0.001440457,0.0004528865,0.0001837933,0.1138029,0.0004122525,0.01130586],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002640131,"threshold_uncertainty_score":0.008832097,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03640453326177989,"score_gpt":0.3225527918107469,"score_spread":0.286148258548967,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}