{"id":"W2135753523","doi":"10.1186/bcr2827","title":"During hormone depletion or tamoxifen treatment of breast cancer cells the estrogen receptor apoprotein supports cell cycling through the retinoic acid receptor α1 apoprotein","year":2011,"lang":"en","type":"article","venue":"Breast Cancer Research","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Cancer Institute; National Institutes of Health; McMaster University","keywords":"Fulvestrant; Tamoxifen; Estrogen receptor; Breast cancer; Cancer research; Internal medicine; Estrogen; Endocrinology; Retinoic acid receptor; Estrogen receptor alpha; Biology; Retinoic acid; Cancer; Medicine; Cell culture","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008935812,0.0002406362,0.000237716,0.0001613771,0.0001142858,0.0002790789,0.0001541926,0.0001652718,0.001810146],"category_scores_gemma":[0.0000790605,0.0000992706,0.0001614466,0.0001371335,0.0001578138,0.0001460404,0.0001433052,0.0003581067,0.0008930792],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000149906,"about_ca_system_score_gemma":0.0001643894,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003024072,"about_ca_topic_score_gemma":0.0005732436,"domain_scores_codex":[0.9998541,0.00002260623,0.00001576986,0.00003793034,0.00004431099,0.00002525241],"domain_scores_gemma":[0.9999224,0.00001513099,0.00002132287,0.00001512467,0.00001151307,0.00001446134],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006901102,0.00001068108,0.0001470206,0.000028305,0.000003290828,0.00002970143,0.00001036698,0.000006461317,0.9986535,0.00003434397,0.00004326023,0.0009639724],"study_design_scores_gemma":[0.0000124791,0.0002505803,0.004734771,0.000008410469,0.00001655037,0.0003556299,0.00002932484,0.0001379056,0.9871383,0.00003268771,0.007280685,0.000002772132],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9825173,0.00694704,0.003930584,0.0002489392,0.00008041011,0.00005963417,0.001219235,0.0002171263,0.004779779],"genre_scores_gemma":[0.9807857,0.003378808,0.00281475,0.0001374944,0.00002720973,0.00009177548,0.002872002,0.00003322271,0.009859054],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001810146,"threshold_uncertainty_score":0.006055474,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03028076446387975,"score_gpt":0.3051682333900629,"score_spread":0.2748874689261832,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}