{"id":"W2135785842","doi":"10.1016/j.molcel.2010.10.024","title":"The MMS22L-TONSL Complex Mediates Recovery from Replication Stress and Homologous Recombination","year":2010,"lang":"en","type":"article","venue":"Molecular Cell","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":142,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; Canada Research Chairs; Ontario Institute for Cancer Research; University Health Network; University of Toronto; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"Canadian Institutes of Health Research","keywords":"Biology; Homologous recombination; RAD51; Control of chromosome duplication; Replication protein A; Origin recognition complex; DNA replication; Eukaryotic DNA replication; DNA re-replication; DNA repair; Genetics; Replication factor C; Minichromosome maintenance; Homologous chromosome; Cell biology; Pre-replication complex; Topoisomerase; DNA; DNA damage; DNA-binding protein; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003863462,0.0005925368,0.0003976581,0.0004234005,0.0004414881,0.00126304,0.0005772738,0.0006904822,0.002526634],"category_scores_gemma":[0.0004000226,0.0004170811,0.0003599445,0.0001663407,0.0004664715,0.0006321676,0.0009446114,0.001041006,0.002272835],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001028907,"about_ca_system_score_gemma":0.0003283835,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005991408,"about_ca_topic_score_gemma":0.0009731798,"domain_scores_codex":[0.9996632,0.00005596131,0.00003549524,0.00006989629,0.00007940133,0.00009602285],"domain_scores_gemma":[0.9996223,0.00003674393,0.00006397019,0.00009533233,0.00004604789,0.0001355382],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001552477,0.00001971236,0.0001871893,0.00002848119,0.000004258424,0.00006341231,0.000010715,0.00006976259,0.9971185,0.0003574259,0.0001894363,0.001795811],"study_design_scores_gemma":[0.000014113,0.00003731716,0.00170723,0.000003846033,0.000002522051,0.0001168044,0.00001980256,0.0009356208,0.9945155,0.00007897845,0.002561359,0.000006939052],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9774181,0.00341774,0.01134597,0.0007452228,0.0001502462,0.00006091308,0.0007492055,0.001240847,0.004871715],"genre_scores_gemma":[0.9884025,0.0002603252,0.002895785,0.0001020696,0.00001606251,0.00003037311,0.001019032,0.0001544336,0.007119494],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002526634,"threshold_uncertainty_score":0.008452475,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005762684578774067,"score_gpt":0.217276629763118,"score_spread":0.2115139451843439,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}