{"id":"W2135930598","doi":"10.2174/187221511797636275","title":"Recent Patents Involving Virus Nucleotide Sequences; Host Defense, RNA Silencing and Expression Vector Strategies","year":2011,"lang":"en","type":"review","venue":"Recent Patents on DNA & Gene Sequences","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Gene silencing; Biology; Virus; Virology; Oncolytic virus; Vector (molecular biology); RNA interference; Gene; RNA silencing; Small interfering RNA; RNA; Computational biology; RNA virus; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009345056,0.001252578,0.001487592,0.0003567321,0.0004576748,0.0003176295,0.001223849,0.0008461561,0.0002722658],"category_scores_gemma":[0.0001840117,0.001003501,0.000412698,0.0004933983,0.0003974702,0.00005338275,0.0005221586,0.0007375463,0.000126786],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002872418,"about_ca_system_score_gemma":0.001111832,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001594259,"about_ca_topic_score_gemma":0.0001909587,"domain_scores_codex":[0.9935105,0.001095347,0.00128319,0.001976561,0.0008639709,0.0012704],"domain_scores_gemma":[0.9969146,0.00007321405,0.0009324099,0.001192448,0.0003630927,0.0005241848],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003783155,0.0001618929,0.00002733719,0.001325963,0.0003156114,0.00006622553,0.0001020379,0.00001285896,0.5029464,0.000008913505,0.0001505867,0.4945039],"study_design_scores_gemma":[0.0007752797,0.003781478,0.00004701146,0.007860302,0.0003225242,0.00006860448,0.0003428863,0.000008829223,0.6697757,0.0001158764,0.3149436,0.001957932],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.1997147,0.797684,0.000006652063,0.00002344309,0.0006134726,0.001271599,0.0002717815,0.00006418229,0.0003502003],"genre_scores_gemma":[0.01014959,0.9878168,0.000183257,0.0001444382,0.0004129362,0.0002399434,0.0006857413,0.0001992195,0.0001681358],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.4925459,"threshold_uncertainty_score":0.9992415,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09271929936098093,"score_gpt":0.3338900954391507,"score_spread":0.2411707960781698,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}