{"id":"W2135930598","doi":"10.2174/187221511797636275","title":"Recent Patents Involving Virus Nucleotide Sequences; Host Defense, RNA Silencing and Expression Vector Strategies","year":2011,"lang":"en","type":"review","venue":"Recent Patents on DNA & Gene Sequences","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Gene silencing; Biology; Virus; Virology; Oncolytic virus; Vector (molecular biology); RNA interference; Gene; RNA silencing; Small interfering RNA; RNA; Computational biology; RNA virus; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006509452,0.001078119,0.0009730431,0.002123368,0.0003646825,0.001124062,0.0008828612,0.001154233,0.009261286],"category_scores_gemma":[0.0005894863,0.0002992201,0.0004906621,0.003063734,0.0005916954,0.001628781,0.0005654187,0.001423625,0.005876262],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009815454,"about_ca_system_score_gemma":0.001240291,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008079223,"about_ca_topic_score_gemma":0.001498519,"domain_scores_codex":[0.9996971,0.00002978778,0.00002860942,0.00004705708,0.0001636802,0.00003391564],"domain_scores_gemma":[0.9997755,0.00008003741,0.00005206838,0.000009616472,0.00005647669,0.00002628029],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007297547,0.00008000415,0.00009894704,0.00659252,0.00003500867,0.000590119,0.00006758035,0.0005163134,0.01299885,0.0135437,0.03372838,0.9316756],"study_design_scores_gemma":[0.00001177109,0.00005908137,0.0001520753,0.0003748595,0.00002504844,0.0009156397,0.0000160007,0.00006305977,0.002408325,0.001315815,0.9946483,0.00000991997],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001224793,0.9720674,0.001795095,0.0009575865,0.001209123,0.00005579888,0.0001155982,0.00005463765,0.02252001],"genre_scores_gemma":[0.004156506,0.977196,0.001662569,0.0005625565,0.0005740174,0.0000525977,0.0002130459,0.000009672744,0.01557299],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.009261286,"threshold_uncertainty_score":0.03098208,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09271929936098093,"score_gpt":0.3338900954391507,"score_spread":0.2411707960781698,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}