{"id":"W2135944439","doi":"10.1073/pnas.0813310106","title":"The role of the <i>CD58</i> locus in multiple sclerosis","year":2009,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":202,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Heart Institute; Université de Montréal","funders":"National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; U.S. Public Health Service; National Institutes of Health; Fonds Wetenschappelijk Onderzoek; Vlaamse regering; European Commission; Multiple Sclerosis Society; Brigham and Women's Hospital; National Institute for Health and Care Research; National Multiple Sclerosis Society","keywords":"Allele; Multiple sclerosis; Peripheral blood mononuclear cell; FOXP3; Locus (genetics); Biology; Central nervous system; Immunology; Genetics; Gene; Endocrinology; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003607857,0.0003553512,0.0003165072,0.000469112,0.0001912833,0.0003731388,0.0004104669,0.0006274951,0.001620043],"category_scores_gemma":[0.0007745484,0.0001401936,0.0001953069,0.0003302913,0.00037682,0.0001314514,0.0002633051,0.0003327134,0.0002540626],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001520253,"about_ca_system_score_gemma":0.0001531676,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008464822,"about_ca_topic_score_gemma":0.0006865619,"domain_scores_codex":[0.999827,0.00005571416,0.00001035013,0.00005473428,0.00003159444,0.000020613],"domain_scores_gemma":[0.9994845,0.0001496618,0.0002255104,0.00002781796,0.00002628166,0.00008603769],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.005861591,0.0002406645,0.3664123,0.0004934512,0.0008471509,0.00412468,0.0003162285,0.001170622,0.5458568,0.001759707,0.001509006,0.07140774],"study_design_scores_gemma":[0.000170052,0.0009721141,0.9717346,0.00008902063,0.0004771654,0.005391067,0.0001125217,0.001698687,0.01466809,0.001922995,0.00274024,0.00002353354],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939473,0.003951046,0.0007748582,0.0003673189,0.0000275685,0.0000068018,0.0001242313,0.00003835927,0.0007624444],"genre_scores_gemma":[0.9978712,0.0008277648,0.000696904,0.0001083425,0.00005203099,0.000005048115,0.00008095631,0.000009576825,0.0003482662],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001620043,"threshold_uncertainty_score":0.005419612,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02826397867984467,"score_gpt":0.241196214397286,"score_spread":0.2129322357174413,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}