{"id":"W2135949348","doi":"10.1128/jb.00832-09","title":"A Novel Insertion Sequence Derepresses Efflux Pump Expression and Preadapts <i>Pseudomonas putida</i> S12 for Extreme Solvent Stress","year":2009,"lang":"en","type":"article","venue":"Journal of Bacteriology","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Efflux; Pseudomonas putida; Biology; Repressor; Solvent; Insertion sequence; Sequence (biology); Genetics; Cell biology; Gene; Biochemistry; Gene expression; Transposable element; Mutant","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001526629,0.0006307374,0.0005650524,0.0003348847,0.0002167998,0.0003268157,0.0003748635,0.0005387389,0.001598617],"category_scores_gemma":[0.0004981632,0.0003343659,0.0006793225,0.0003212919,0.000361431,0.0001951571,0.0003968214,0.001047428,0.0008968082],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003763291,"about_ca_system_score_gemma":0.0005823672,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001144952,"about_ca_topic_score_gemma":0.001810119,"domain_scores_codex":[0.9997002,0.00004573644,0.00005565559,0.000052175,0.00008031008,0.0000659174],"domain_scores_gemma":[0.9994137,0.000129027,0.0001761703,0.00008348501,0.00006359957,0.0001339829],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001528219,0.00006893143,0.0002397548,0.0000283944,0.000006281052,0.0001964048,0.00003177661,0.00006168387,0.9964995,0.0001006404,0.00004163514,0.002572215],"study_design_scores_gemma":[0.00005943386,0.001468029,0.01112599,0.00002600523,0.00008560925,0.002002117,0.0001399683,0.00141284,0.9791722,0.00009125686,0.004376936,0.00003976434],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9887184,0.000206324,0.009085612,0.0001506813,0.0000799646,0.0001091407,0.0004173851,0.0003250802,0.0009074918],"genre_scores_gemma":[0.983796,0.0002611964,0.01097343,0.0001492621,0.00005362462,0.00009130786,0.002175949,0.0001413036,0.002357987],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001598617,"threshold_uncertainty_score":0.005347967,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02708013773359095,"score_gpt":0.2595849201273339,"score_spread":0.2325047823937429,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}