{"id":"W2135949348","doi":"10.1128/jb.00832-09","title":"A Novel Insertion Sequence Derepresses Efflux Pump Expression and Preadapts <i>Pseudomonas putida</i> S12 for Extreme Solvent Stress","year":2009,"lang":"en","type":"article","venue":"Journal of Bacteriology","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Efflux; Pseudomonas putida; Biology; Repressor; Solvent; Insertion sequence; Sequence (biology); Genetics; Cell biology; Gene; Biochemistry; Gene expression; Transposable element; Mutant","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002120172,0.0001956172,0.0003243067,0.00008112121,0.00007508968,0.00003250182,0.0002433496,0.0004207191,0.000006441477],"category_scores_gemma":[0.0001374789,0.0001589803,0.0001144425,0.00004472646,0.0001198289,0.00001311634,0.00009637165,0.0001495311,4.998561e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001601342,"about_ca_system_score_gemma":0.00008768152,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004635242,"about_ca_topic_score_gemma":0.000009240342,"domain_scores_codex":[0.9988144,0.00005324369,0.0004750029,0.0002989346,0.00008058747,0.0002778084],"domain_scores_gemma":[0.9989873,0.00002801871,0.0004367417,0.0002358051,0.0002078999,0.0001042245],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005386613,0.0001419402,0.0006643588,0.00002076693,0.00003882666,0.000004126618,0.00002223243,0.00002106121,0.9934349,0.00004800316,0.0001879572,0.004877183],"study_design_scores_gemma":[0.001295434,0.002292196,0.01351841,0.00007637835,0.00003797078,0.0005891059,0.00002547231,0.00002977431,0.9702685,0.0003489831,0.01132763,0.0001901348],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9898462,0.0006794848,0.007936681,0.0009075862,0.0003517167,0.0002059272,0.00004398575,0.000007752692,0.00002069734],"genre_scores_gemma":[0.9912422,0.0009074762,0.006963331,0.0003111814,0.0004649358,0.00000781561,0.00004562885,0.00001475149,0.00004268935],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02316638,"threshold_uncertainty_score":0.6483029,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02708013773359095,"score_gpt":0.2595849201273339,"score_spread":0.2325047823937429,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}