{"id":"W2135956175","doi":"10.1124/jpet.104.070805","title":"Inhibitory Profile of SEA0400 [2-[4-[(2,5-Difluorophenyl)methoxy]phenoxy]-5-ethoxyaniline] Assessed on the Cardiac Na+-Ca2+ Exchanger, NCX1.1","year":2004,"lang":"en","type":"article","venue":"Journal of Pharmacology and Experimental Therapeutics","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":60,"is_retracted":false,"has_abstract":false,"ca_institutions":"St. Boniface Hospital","funders":"","keywords":"Isotopes of calcium; Ion exchange; Kinetics; Chemistry; Biophysics; Ion; Physics; Calcium; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002005306,0.000429599,0.0004800956,0.0001942817,0.0001876034,0.0002218997,0.0004352952,0.0005125668,0.003869192],"category_scores_gemma":[0.0003869145,0.000193572,0.0002889423,0.0001806712,0.0002990943,0.0002449354,0.000156274,0.000522972,0.0005931301],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001917559,"about_ca_system_score_gemma":0.0004135049,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00117515,"about_ca_topic_score_gemma":0.002029146,"domain_scores_codex":[0.9998534,0.0000447546,0.00001623379,0.00002160578,0.00002131691,0.00004273887],"domain_scores_gemma":[0.9998021,0.00006483142,0.00002665102,0.00002260142,0.00002823558,0.00005563716],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.006126112,0.0004782339,0.0004296545,0.000147637,0.00003163698,0.0001566393,0.00008233821,0.000337931,0.9847607,0.0002119483,0.0006626914,0.006574544],"study_design_scores_gemma":[0.0004883601,0.0119218,0.009818399,0.00002238507,0.00006577293,0.000323126,0.00008381215,0.001330133,0.9728568,0.00006692343,0.003001059,0.00002141608],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9903675,0.003274338,0.0005879364,0.0002107606,0.0001294267,0.00005986191,0.0007171204,0.0001581768,0.00449496],"genre_scores_gemma":[0.9918183,0.002204061,0.0007551513,0.00008797083,0.00006208071,0.00005044855,0.0009867405,0.00002357458,0.004011583],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003869192,"threshold_uncertainty_score":0.0129438,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03095703948336659,"score_gpt":0.3284186927991217,"score_spread":0.2974616533157551,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}