{"id":"W2135958915","doi":"10.1186/1471-2407-11-6","title":"Behavioral and psychosocial effects of rapid genetic counseling and testing in newly diagnosed breast cancer patients: Design of a multicenter randomized clinical trial","year":2011,"lang":"en","type":"article","venue":"BMC Cancer","topic":"BRCA gene mutations in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research","funders":"Lombardi Comprehensive Cancer Center, Georgetown University; Georgetown University","keywords":"Medicine; Psychosocial; Breast cancer; Genetic counseling; Genetic testing; Randomized controlled trial; Prophylactic Mastectomy; Mastectomy; Worry; Distress; Prophylactic Surgery; Quality of life (healthcare); Surgical oncology; Gynecology; Physical therapy; Cancer; Internal medicine; Anxiety; Psychiatry; Clinical psychology; Nursing","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01452386,0.003813874,0.00581807,0.001058459,0.001114415,0.001964741,0.002814328,0.00558846,0.00981166],"category_scores_gemma":[0.01499311,0.001790375,0.004051183,0.000899497,0.003250916,0.002253978,0.001489077,0.003963343,0.001271937],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001612875,"about_ca_system_score_gemma":0.003562605,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001518773,"about_ca_topic_score_gemma":0.001503125,"domain_scores_codex":[0.9853139,0.01094102,0.0008907643,0.001179849,0.0006688647,0.001005541],"domain_scores_gemma":[0.9884803,0.005299823,0.002440915,0.0008654039,0.0008674763,0.002045964],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9853651,0.01130089,0.0004927755,0.0002528312,0.0005595842,0.00001557663,0.00003155642,0.0001290584,0.0002690514,0.00004081691,0.00009680809,0.00144603],"study_design_scores_gemma":[0.9295202,0.06877325,0.0006216313,0.00002241342,0.0004543891,0.000006510292,0.00001902244,0.0002628367,0.000118849,0.00007039878,0.0001215685,0.000008786014],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"protocol","genre_scores_codex":[0.9282266,0.001689068,0.001562202,0.0008378057,0.001281263,0.06393597,0.0008470755,0.0001052237,0.001514754],"genre_scores_gemma":[0.8350914,0.001172487,0.007038094,0.001565922,0.001293713,0.1501458,0.0007547403,0.00002310778,0.002914645],"genre_candidate":"protocol","genre_consensus":null,"teacher_disagreement_score":0.01452386,"threshold_uncertainty_score":0.07681048,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04893275732957583,"score_gpt":0.3457510788305735,"score_spread":0.2968183215009977,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}