{"id":"W2135960565","doi":"10.1128/iai.70.9.5269-5273.2002","title":"Mixed Periodontal Th1-Th2 Cytokine Profile in <i>Actinobacillus actinomycetemcomitans</i> -Specific Osteoprotegerin Ligand (or RANK-L)- Mediated Alveolar Bone Destruction In Vivo","year":2002,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Bone Metabolism and Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"London Health Sciences Centre; Lawson Health Research Institute; Western University","funders":"National Institute of Dental and Craniofacial Research; Canadian Institutes of Health Research; National Institutes of Health; University of Toronto","keywords":"Osteoprotegerin; Actinobacillus; Dental alveolus; In vivo; Periodontitis; Biology; Immunology; Periodontal pathogen; Cytokine; Microbiology; Medicine; Receptor; Dentistry; Porphyromonas gingivalis; Activator (genetics)","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002399082,0.0002214896,0.000262198,0.0001527852,0.0001503034,0.00005612048,0.00006882803,0.0002124039,0.0002274622],"category_scores_gemma":[0.0001774614,0.0002055525,0.00007375093,0.0002925721,0.0001027292,0.00003911396,0.00007817398,0.0002639261,0.00001323499],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004783433,"about_ca_system_score_gemma":0.00003100494,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001164342,"about_ca_topic_score_gemma":0.001760485,"domain_scores_codex":[0.9987422,0.0002284704,0.0003370764,0.0003133466,0.0001100062,0.0002689149],"domain_scores_gemma":[0.9994304,0.00003163122,0.0001045725,0.0002818156,0.00005094519,0.0001006186],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007404416,0.0003551153,0.05914332,0.00004146421,0.00001980201,0.00001709478,0.0001870757,0.000005693599,0.9291108,0.00001139361,0.0003539407,0.01001391],"study_design_scores_gemma":[0.005906119,0.0004730602,0.3562188,0.00006251095,0.00002475977,0.0002902491,0.0005871478,0.000158228,0.5879045,0.00001316675,0.04779932,0.0005621967],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996377,0.001501938,0.00003415336,0.00004503933,0.0002882539,0.0003974861,0.0000540707,0.00003198051,0.001270102],"genre_scores_gemma":[0.9964729,0.002871492,0.00009000591,0.00006118495,0.0001065036,0.00007146072,0.00008645553,0.00002056384,0.0002194665],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3412063,"threshold_uncertainty_score":0.8382186,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01792068036170778,"score_gpt":0.2167408416274018,"score_spread":0.198820161265694,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}