{"id":"W2135975326","doi":"10.2217/imt.14.66","title":"Vedolizumab for Ulcerative Colitis and Crohn’s Disease: Results and Implications of GEMINI Studies","year":2014,"lang":"en","type":"article","venue":"Immunotherapy","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"Vancouver Coastal Health","funders":"","keywords":"Vedolizumab; Ulcerative colitis; Medicine; Inflammatory bowel disease; Internal medicine; Gastroenterology; Crohn's disease; Placebo; Maintenance therapy; Disease; Immunology; Pathology; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001248853,0.00009397732,0.000110492,0.00001825046,0.0000906098,0.00001231167,0.00005978471,0.00003990061,0.000001158285],"category_scores_gemma":[0.0001751784,0.00008705756,0.00003699022,0.00001715847,0.0001847809,0.000003556014,0.00002954743,0.00001850769,3.487411e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006719672,"about_ca_system_score_gemma":0.00003763902,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002784777,"about_ca_topic_score_gemma":0.00001735522,"domain_scores_codex":[0.9994496,0.00004282413,0.0001631644,0.000200792,0.00003623172,0.0001074363],"domain_scores_gemma":[0.9994179,0.00004595405,0.0001028117,0.0002539555,0.0001310578,0.00004830934],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.06041318,0.0005824985,0.04063427,0.001111558,0.002691937,0.0000190012,0.006897938,0.00005543164,0.5340439,0.06962138,0.02054527,0.2633836],"study_design_scores_gemma":[0.002336478,0.0001477594,0.9719377,0.00002134668,0.00002052968,0.000001901184,0.00009302868,0.00003322182,0.00380953,0.001667734,0.01980391,0.0001268807],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953609,0.002973344,0.0004337084,0.0003462658,0.00003903381,0.0003618487,0.000309117,0.000007177654,0.0001686126],"genre_scores_gemma":[0.9969239,0.001808498,0.0004447185,0.000239629,0.00007481848,0.0001408611,0.00005984866,0.00001541759,0.0002922684],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9313034,"threshold_uncertainty_score":0.3550104,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01453315354671545,"score_gpt":0.2979342926323513,"score_spread":0.2834011390856359,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}