{"id":"W2136020004","doi":"10.1093/humrep/deh252","title":"Synergistic effects between FSH and 1,1-dichloro-2,2-bis(P-chlorophenyl)ethylene (P,P'-DDE) on human granulosa cell aromatase activity","year":2004,"lang":"en","type":"article","venue":"Human Reproduction","topic":"Effects and risks of endocrine disrupting chemicals","field":"Environmental Science","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; McMaster University Medical Centre","funders":"Hamilton Health Sciences","keywords":"Aromatase; Granulosa cell; Follicular fluid; Internal medicine; Endocrinology; Androstenedione; Chemistry; Follicular phase; Enzyme assay; Ovarian follicle; Basal (medicine); Enzyme; Biology; Oocyte; Biochemistry; Hormone; Embryo; Medicine; Cell biology; Androgen","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002293383,0.0003214335,0.0004350527,0.0001645077,0.0001845286,0.0002645792,0.0001368851,0.0002235905,0.001228083],"category_scores_gemma":[0.000382146,0.000156801,0.0003436984,0.0001490154,0.0002880133,0.0001180755,0.0002721279,0.0001892316,0.0002284879],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000243369,"about_ca_system_score_gemma":0.0002502598,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007232499,"about_ca_topic_score_gemma":0.001730231,"domain_scores_codex":[0.9997279,0.00009291546,0.00002523533,0.00004150992,0.00006324306,0.00004912099],"domain_scores_gemma":[0.9997738,0.0001139084,0.00003224793,0.0000185063,0.00002693457,0.00003450051],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001371345,0.00006671489,0.002812034,0.0001630398,0.00003818136,0.0002697025,0.00004226702,0.0002292611,0.9908009,0.00003177232,0.00008599249,0.004088882],"study_design_scores_gemma":[0.00005610392,0.002619591,0.02292,0.00001171565,0.00009792996,0.0008045337,0.00009064515,0.0004184767,0.9705313,0.00002753276,0.002414434,0.000007787122],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993122,0.004624684,0.0006329347,0.00008887789,0.00004268945,0.00003002873,0.0001621371,0.00001900643,0.001277597],"genre_scores_gemma":[0.996294,0.001743225,0.0009291148,0.00005845124,0.00003270336,0.00002533746,0.0001685405,0.000004133758,0.0007446057],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001228083,"threshold_uncertainty_score":0.004108369,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01685067588097292,"score_gpt":0.3290719070524011,"score_spread":0.3122212311714282,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}