{"id":"W2136020004","doi":"10.1093/humrep/deh252","title":"Synergistic effects between FSH and 1,1-dichloro-2,2-bis(P-chlorophenyl)ethylene (P,P'-DDE) on human granulosa cell aromatase activity","year":2004,"lang":"en","type":"article","venue":"Human Reproduction","topic":"Effects and risks of endocrine disrupting chemicals","field":"Environmental Science","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; McMaster University Medical Centre","funders":"Hamilton Health Sciences","keywords":"Aromatase; Granulosa cell; Follicular fluid; Internal medicine; Endocrinology; Androstenedione; Chemistry; Follicular phase; Enzyme assay; Ovarian follicle; Basal (medicine); Enzyme; Biology; Oocyte; Biochemistry; Hormone; Embryo; Medicine; Cell biology; Androgen","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004533593,0.0003485525,0.0003604224,0.00007302121,0.0009544787,0.0000626859,0.0002166894,0.0001082011,0.00009422604],"category_scores_gemma":[0.0001598644,0.0003106593,0.00009463076,0.000180033,0.0003436789,0.0002035703,0.0003573709,0.0003599501,0.0001263385],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002052705,"about_ca_system_score_gemma":0.000006821373,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001459208,"about_ca_topic_score_gemma":0.00005061809,"domain_scores_codex":[0.9974984,0.00009940832,0.0002814635,0.001231425,0.0004388922,0.0004504064],"domain_scores_gemma":[0.9985874,0.0001012525,0.0002046975,0.0008953125,0.00001194747,0.0001994184],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003026207,0.0004014731,0.005583357,0.0001558453,0.00001883795,0.00004040953,0.0002342017,0.0004528874,0.9866534,0.0001273575,0.0004121399,0.005889867],"study_design_scores_gemma":[0.001164762,0.000587817,0.1539976,0.00009170994,0.00009582328,0.00001014564,0.00002143942,0.000003154581,0.838751,0.004024338,0.0007895472,0.0004626346],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962532,0.00008078699,0.00004003362,0.0002237033,0.0002124654,0.0004990962,0.00001180972,0.0001972097,0.002481675],"genre_scores_gemma":[0.9984524,0.00001839188,0.000185546,0.00004258175,0.0006426541,0.00003894146,0.00006771801,0.00004575655,0.0005060167],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1484143,"threshold_uncertainty_score":0.9999346,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01685067588097292,"score_gpt":0.3290719070524011,"score_spread":0.3122212311714282,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}