{"id":"W2136092734","doi":"10.1176/ajp.2006.163.10.1826","title":"Effect of 5-HT<sub>1A</sub>Receptor Gene Polymorphism on Negative and Depressive Symptom Response to Antipsychotic Treatment of Drug-Naive Psychotic Patients","year":2006,"lang":"en","type":"article","venue":"American Journal of Psychiatry","topic":"Neurotransmitter Receptor Influence on Behavior","field":"Neuroscience","cited_by":108,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Antipsychotic drug; Antipsychotic; Drug-naïve; Polymorphism (computer science); Depressive symptoms; Drug; Psychiatry; Medicine; Atypical antipsychotic; Major depressive disorder; Psychology; Pharmacology; Internal medicine; Schizophrenia (object-oriented programming); Gene; Genetics; Genotype; Biology; Anxiety","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002538298,0.0004713355,0.0009497795,0.000659659,0.00009865283,0.00002896037,0.0004239042,0.0000560577,0.00002242422],"category_scores_gemma":[0.000141277,0.0003764498,0.000344087,0.0008085422,0.0006413133,0.0001959539,0.00002312744,0.0002350806,0.00002390194],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001111344,"about_ca_system_score_gemma":0.0001456775,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005266262,"about_ca_topic_score_gemma":0.000005067795,"domain_scores_codex":[0.9958715,0.001317028,0.001037281,0.0005719693,0.0007651394,0.0004370669],"domain_scores_gemma":[0.9963361,0.001105147,0.001622727,0.0004579793,0.0001601069,0.0003179189],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01448446,0.001410413,0.1841342,0.00002923205,0.00004620664,0.00001965721,0.0005323633,0.00009183493,0.7816112,0.00001439222,0.0002560857,0.01736995],"study_design_scores_gemma":[0.004211191,0.02204617,0.1988533,0.0002811974,0.0001547298,0.00005266429,0.00004594909,0.000002151506,0.7740257,0.00005034895,0.00001798585,0.0002586654],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970165,0.0001212721,0.00004587275,0.0006046312,0.001301852,0.000753495,0.0001181847,0.00001756299,0.00002055911],"genre_scores_gemma":[0.9984415,0.000113738,0.0008161233,0.0003948215,0.0001296127,0.0000241301,0.000001095559,0.00006465674,0.00001432149],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02063576,"threshold_uncertainty_score":0.9998688,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005615697613690496,"score_gpt":0.2582573081754767,"score_spread":0.2526416105617862,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}