{"id":"W2136141730","doi":"10.1186/1477-7827-12-123","title":"IGFBP-4 and −5 are expressed in first-trimester villi and differentially regulate the migration of HTR-8/SVneo cells","year":2014,"lang":"en","type":"article","venue":"Reproductive Biology and Endocrinology","topic":"Pregnancy and preeclampsia studies","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Mount Sinai Hospital; Child and Family Research Institute; Lunenfeld-Tanenbaum Research Institute; Simon Fraser University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Simon Fraser University","keywords":"Trophoblast; Placenta; Insulin-like growth factor-binding protein; Placentation; Biology; Intrauterine growth restriction; Placental growth factor; Growth factor; Proteases; Endocrinology; Internal medicine; Insulin-like growth factor; Andrology; Placental insufficiency; Cell growth; Preeclampsia; Pregnancy; Receptor; Medicine; Fetus; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001527053,0.0001322526,0.0003713023,0.00007261652,0.00008797482,0.000003234852,0.00004182342,0.0001031124,0.000005201337],"category_scores_gemma":[0.0001580885,0.00008444845,0.00002335106,0.00004978933,0.0007258045,0.00003419218,0.0001142746,0.0001541577,6.349057e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005212034,"about_ca_system_score_gemma":0.000007751843,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001118491,"about_ca_topic_score_gemma":0.0002057545,"domain_scores_codex":[0.9989191,0.0001971076,0.0001986759,0.0004542735,0.00002922271,0.0002016458],"domain_scores_gemma":[0.9993121,0.0002229075,0.0001055964,0.000291515,0.00004206458,0.00002581842],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0007786615,0.00009466102,0.8619726,0.0002250158,0.0001791194,0.000008772689,0.002929606,0.000002090931,0.1208264,0.004517937,0.0001962772,0.008268854],"study_design_scores_gemma":[0.001215773,0.0003913192,0.9482673,0.00008762556,0.00006912915,0.00009959599,0.0002433431,0.00002397533,0.03815275,0.004629142,0.006719884,0.0001001671],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9848022,0.007066039,0.00005139931,0.007352064,0.0001229682,0.0002652861,0.000006243552,0.00001366235,0.0003201066],"genre_scores_gemma":[0.9936994,0.005791391,0.00009085388,0.0001292393,0.0001024705,0.00002631497,0.000004986315,0.000005806841,0.000149547],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08629468,"threshold_uncertainty_score":0.3443708,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01552865997128936,"score_gpt":0.2537292885976327,"score_spread":0.2382006286263434,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}