{"id":"W2136145926","doi":"10.1128/mcb.00272-15","title":"Mutagenesis of ARS2 Domains To Assess Possible Roles in Cell Cycle Progression and MicroRNA and Replication-Dependent Histone mRNA Biogenesis","year":2015,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria","funders":"","keywords":"Biology; Zinc finger; RNA polymerase II; RNA; Genetics; Cell biology; RNA-binding protein; Drosha; Gene expression; RNA interference; Gene; Transcription factor; Promoter","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003967884,0.0007104466,0.0003229306,0.0002786923,0.0003069745,0.0002405842,0.0005766557,0.0004726244,0.002149092],"category_scores_gemma":[0.0003076178,0.0002608531,0.0006025301,0.0002667901,0.0003656773,0.0002013444,0.0002875161,0.000848453,0.0006605127],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006419837,"about_ca_system_score_gemma":0.0004947973,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00178065,"about_ca_topic_score_gemma":0.002536227,"domain_scores_codex":[0.9997978,0.00006315671,0.00002552796,0.00003239503,0.00005045877,0.00003079213],"domain_scores_gemma":[0.9996637,0.0001496798,0.0000647667,0.00003317842,0.00003734073,0.00005143187],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004639411,0.0001182161,0.0006280488,0.00009232812,0.00003177183,0.0004258924,0.00005585092,0.0009199615,0.9951987,0.0004609191,0.00007320281,0.001531143],"study_design_scores_gemma":[0.0001310577,0.0004422711,0.005341948,0.00002566546,0.00009539277,0.001100887,0.00008682042,0.00634727,0.9790637,0.0001671772,0.00717457,0.00002324706],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9861982,0.0007802179,0.009663806,0.0001306829,0.00008090125,0.0001580496,0.0006429016,0.00007637904,0.002268829],"genre_scores_gemma":[0.9913994,0.0002827025,0.005813738,0.00009665862,0.00001246104,0.00007525463,0.0008215709,0.0000606937,0.001437534],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002149092,"threshold_uncertainty_score":0.007189453,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01519773136036927,"score_gpt":0.299830799169148,"score_spread":0.2846330678087787,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}