{"id":"W2136155663","doi":"10.1182/blood.v97.5.1343","title":"SHIP's C-terminus is essential for its hydrolysis of PIP3 and inhibition of mast cell degranulation","year":2001,"lang":"en","type":"article","venue":"Blood","topic":"Mast cells and histamine","field":"Immunology and Microbiology","cited_by":71,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Degranulation; Mast cell; Cell biology; Phosphorylation; Phosphatase; Biochemistry; Chemistry; Biology; Immunology; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006424281,0.00007031775,0.0001669259,0.00006803463,0.00004279198,0.000002593112,0.00003154278,0.0001078783,0.0003177422],"category_scores_gemma":[0.000006640659,0.00006785429,0.00005549264,0.00005662523,0.00005884686,0.00003506217,0.00001711469,0.00003680314,0.000007236827],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00000213254,"about_ca_system_score_gemma":0.000009128486,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002704445,"about_ca_topic_score_gemma":0.00002058694,"domain_scores_codex":[0.999531,0.00002057219,0.0002000214,0.0001254136,0.00001818317,0.0001047823],"domain_scores_gemma":[0.999692,0.00003137828,0.0001264675,0.00008728765,0.00005403511,0.000008812603],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000100499,0.0003142523,0.001925724,0.0001102029,0.00003969984,0.000001568221,0.0002691972,0.000001188527,0.9960473,0.00009760589,0.0001163615,0.0009764148],"study_design_scores_gemma":[0.002892786,0.0001820726,0.002520507,0.00001918579,0.0001899958,0.00001851419,0.00003342237,0.00002344927,0.9917467,0.00006388292,0.002239444,0.00007002724],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970445,0.001281051,0.0002637595,0.0000368202,0.00006088945,0.0001468474,0.00007524744,0.000007229684,0.001083635],"genre_scores_gemma":[0.9979532,0.00008308611,0.00009478287,0.00001310553,0.00001932403,0.000006883376,0.000111744,0.000006540369,0.001711355],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004300572,"threshold_uncertainty_score":0.3479054,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008356873920784174,"score_gpt":0.2059443007445702,"score_spread":0.197587426823786,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}