{"id":"W2136164716","doi":"10.1084/jem.20091704","title":"Survival effect of PDGF-CC rescues neurons from apoptosis in both brain and retina by regulating GSK3β phosphorylation","year":2010,"lang":"en","type":"article","venue":"The Journal of Experimental Medicine","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":121,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"National Institutes of Health","keywords":"Platelet-derived growth factor receptor; Neuroprotection; Biology; GSK-3; Cell biology; Growth factor; Phosphorylation; Neurodegeneration; Platelet-derived growth factor; Axotomy; Neuroscience; Receptor; Internal medicine; Medicine; Central nervous system; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001062186,0.0003021507,0.0002296564,0.000220892,0.0001401782,0.0002073176,0.0001251727,0.0001595287,0.0007328256],"category_scores_gemma":[0.0001168013,0.00007901505,0.0001795543,0.0001422463,0.000155619,0.0001100338,0.0001685838,0.000451001,0.0002665462],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001728919,"about_ca_system_score_gemma":0.0003580323,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009009753,"about_ca_topic_score_gemma":0.00127936,"domain_scores_codex":[0.999922,0.00001144857,0.000009237307,0.00001068803,0.00002449566,0.00002209605],"domain_scores_gemma":[0.9999391,0.000007421421,0.00001747378,0.000009136394,0.00001038864,0.00001645619],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002028814,0.000027567,0.00009548837,0.00006778272,0.000008274274,0.0000751665,0.00001409659,0.00007843004,0.9953957,0.0001024449,0.00009191157,0.003840206],"study_design_scores_gemma":[0.00007982206,0.0006051479,0.003482803,0.00001524723,0.00003460984,0.0003522469,0.00003026443,0.0007489788,0.9916801,0.0001224094,0.002843629,0.000004714901],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9908181,0.004538954,0.001640362,0.0001746988,0.00003762356,0.00002983504,0.000242524,0.0001239776,0.002393797],"genre_scores_gemma":[0.9937231,0.002422782,0.001605813,0.00005099412,0.00001616824,0.00003713243,0.0003602024,0.0000195896,0.001764379],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009009753,"threshold_uncertainty_score":0.002451599,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005177586247348254,"score_gpt":0.2609264732299429,"score_spread":0.2557488869825947,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}