{"id":"W2136196337","doi":"10.1128/aac.01388-08","title":"In Vitro Activity of Iclaprim against Respiratory and Bacteremic Isolates of <i>Streptococcus pneumoniae</i>","year":2009,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Pneumonia and Respiratory Infections","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"","keywords":"Trimethoprim; Streptococcus pneumoniae; Sulfamethoxazole; Microbiology; Dihydrofolate reductase; Pneumococcal infections; Biology; Antibacterial agent; Antibiotics; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002910053,0.0004436706,0.0004103485,0.0001493724,0.0001413301,0.0003827933,0.0002791393,0.0003365141,0.001322153],"category_scores_gemma":[0.0005431903,0.0001616894,0.0002091932,0.0001557098,0.0002171981,0.0001473063,0.0001573386,0.000397258,0.000512121],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000249138,"about_ca_system_score_gemma":0.0002816415,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001421995,"about_ca_topic_score_gemma":0.001830503,"domain_scores_codex":[0.9996892,0.0001302784,0.00002266582,0.00004352873,0.00005894943,0.00005535463],"domain_scores_gemma":[0.9997299,0.0001154252,0.00004743173,0.00002350844,0.00003751211,0.00004614421],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002771595,0.0005288746,0.00216526,0.0005081408,0.00005736803,0.0001588513,0.0001182381,0.0007396135,0.9711089,0.0001232869,0.0009219037,0.02079774],"study_design_scores_gemma":[0.0002759652,0.01251259,0.0112514,0.00009164048,0.0001162244,0.001599427,0.00005008638,0.002228303,0.9655508,0.00004477263,0.006259779,0.00001898926],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.974457,0.01795517,0.00146897,0.0001645736,0.0001117174,0.00006525544,0.0007321073,0.0000943733,0.004950824],"genre_scores_gemma":[0.9924276,0.003160082,0.001840828,0.0001075688,0.00006767947,0.00002609605,0.001315928,0.00001222852,0.001041977],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001421995,"threshold_uncertainty_score":0.004423022,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01252061040991811,"score_gpt":0.2678329943268922,"score_spread":0.2553123839169741,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}