{"id":"W2136236728","doi":"10.1016/s0140-6736(09)61248-4","title":"Efficacy of human papillomavirus (HPV)-16/18 AS04-adjuvanted vaccine against cervical infection and precancer caused by oncogenic HPV types (PATRICIA): final analysis of a double-blind, randomised study in young women","year":2009,"lang":"en","type":"article","venue":"The Lancet","topic":"Cervical Cancer and HPV Research","field":"Medicine","cited_by":1655,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba; University of Alberta","funders":"GlaxoSmithKline","keywords":"Medicine; Cohort; Interim analysis; Cervical cancer; Vaccine efficacy; Clinical endpoint; Vaccine trial; Population; HPV infection; Internal medicine; Cervical intraepithelial neoplasia; Vaccination; HPV vaccines; Clinical trial; Oncology; Cancer; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004526998,0.001946731,0.00653998,0.0009208166,0.0005353009,0.001006197,0.001652084,0.003397085,0.004265609],"category_scores_gemma":[0.00501863,0.001392033,0.003380525,0.0008288165,0.002160366,0.001207154,0.0005815529,0.002543235,0.0007760252],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009739593,"about_ca_system_score_gemma":0.001694335,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002883027,"about_ca_topic_score_gemma":0.002978428,"domain_scores_codex":[0.9969495,0.001915289,0.0002962866,0.0003434471,0.0001832109,0.0003122381],"domain_scores_gemma":[0.9970683,0.001379417,0.0004240157,0.0003623297,0.000197731,0.0005681938],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9879547,0.002684218,0.0003019015,0.0004441312,0.0007069989,0.00002231778,0.00005853928,0.0001414249,0.001553053,0.00002752849,0.00009177923,0.006013309],"study_design_scores_gemma":[0.8397304,0.1562647,0.001911373,0.00002815546,0.0009957651,0.00002071927,0.00002078466,0.0001479362,0.0005956996,0.00005265895,0.0002156405,0.00001615808],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9927954,0.003131841,0.0004824479,0.00019337,0.0003550542,0.001945368,0.000442243,0.00008151477,0.0005727845],"genre_scores_gemma":[0.9915413,0.002269055,0.001327682,0.0002969044,0.0003604396,0.001774833,0.0004642726,0.00002892616,0.001936655],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00653998,"threshold_uncertainty_score":0.02394134,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06978511801361202,"score_gpt":0.3836301452817176,"score_spread":0.3138450272681056,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}