{"id":"W2136271640","doi":"10.1128/mcb.23.22.8363-8376.2003","title":"Human Heterochromatin Protein 1 Isoforms HP1 <sup>Hsα</sup> and HP1 <sup>Hsβ</sup> Interfere with hTERT-Telomere Interactions and Correlate with Changes in Cell Growth and Response to Ionizing Radiation","year":2003,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":92,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke; Columbia College","funders":"National Institute of Neurological Disorders and Stroke; National Cancer Institute; National Institutes of Health","keywords":"Heterochromatin; Biology; Heterochromatin protein 1; Telomere; Ionizing radiation; Molecular biology; Physics; Genetics; Irradiation; DNA; Chromatin; Nuclear physics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002683217,0.0003905948,0.0005217505,0.0004312226,0.0002104366,0.00007026782,0.00007009288,0.0002031224,0.00002304498],"category_scores_gemma":[0.00007627557,0.000297367,0.00003069927,0.0002824164,0.0002679776,0.000114206,0.00007658801,0.0003731628,0.000003118072],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004637956,"about_ca_system_score_gemma":0.00004983,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001514296,"about_ca_topic_score_gemma":0.0001236945,"domain_scores_codex":[0.9980515,0.0003315868,0.0003286169,0.0006992619,0.000128487,0.0004605637],"domain_scores_gemma":[0.9992021,0.00006672967,0.0001151463,0.0002697479,0.00006241621,0.0002839015],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001602916,0.0001537477,0.03726933,0.0003395046,0.00009496915,0.0003596465,0.00569242,0.0000231134,0.9509036,0.0002759804,0.00001171935,0.003273058],"study_design_scores_gemma":[0.0166336,0.01608766,0.06064007,0.002273837,0.0004622324,0.003316476,0.01096474,0.003067207,0.8810824,0.0004627949,0.002789579,0.002219432],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947639,0.001919374,0.00143998,0.0006940531,0.00001864243,0.0009631109,0.00001151213,0.00004406152,0.0001454176],"genre_scores_gemma":[0.9980214,0.000137597,0.001021391,0.0003899178,0.00002574291,0.00009731525,0.00005174761,0.00004873165,0.0002061303],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06982122,"threshold_uncertainty_score":0.9999478,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007189883622478598,"score_gpt":0.2252696516291553,"score_spread":0.2180797680066767,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}