{"id":"W2136271640","doi":"10.1128/mcb.23.22.8363-8376.2003","title":"Human Heterochromatin Protein 1 Isoforms HP1 <sup>Hsα</sup> and HP1 <sup>Hsβ</sup> Interfere with hTERT-Telomere Interactions and Correlate with Changes in Cell Growth and Response to Ionizing Radiation","year":2003,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":92,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke; Columbia College","funders":"National Institute of Neurological Disorders and Stroke; National Cancer Institute; National Institutes of Health","keywords":"Heterochromatin; Biology; Heterochromatin protein 1; Telomere; Ionizing radiation; Molecular biology; Physics; Genetics; Irradiation; DNA; Chromatin; Nuclear physics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001128172,0.0003229598,0.000128559,0.0001203206,0.00008367059,0.0001838293,0.000137166,0.0001450529,0.001033123],"category_scores_gemma":[0.00008293114,0.0001137159,0.0001500464,0.0001190254,0.0001590398,0.0001003442,0.0001284055,0.0003715248,0.0003913207],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000143744,"about_ca_system_score_gemma":0.00008527548,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003218787,"about_ca_topic_score_gemma":0.0003625519,"domain_scores_codex":[0.9999088,0.00001666622,0.000008006355,0.00001913038,0.0000328445,0.00001451858],"domain_scores_gemma":[0.9999107,0.00001717596,0.0000271728,0.00001623395,0.000007498249,0.00002116547],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005949436,0.00001135298,0.0002273538,0.00001445097,0.000005081933,0.00001838418,0.000004261822,0.00002681792,0.998613,0.00003908778,0.00003301336,0.0009476169],"study_design_scores_gemma":[0.000007777171,0.0002010942,0.009003877,0.00000253616,0.00001304558,0.0004603965,0.00001170708,0.0003808829,0.9868067,0.0000264251,0.003083716,0.000001853402],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935893,0.002136242,0.002519654,0.00006355556,0.00002058993,0.00002166254,0.0004488449,0.00007430575,0.001125792],"genre_scores_gemma":[0.9895216,0.001421177,0.002420712,0.00004713695,0.00001156781,0.0000342976,0.002341842,0.00002854103,0.004173157],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001033123,"threshold_uncertainty_score":0.003456175,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007189883622478598,"score_gpt":0.2252696516291553,"score_spread":0.2180797680066767,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}