{"id":"W2136298823","doi":"10.1046/j.1365-2249.2001.01492.x","title":"Inhibition of HIV-1-mediated syncytium formation and virus replication by the lipophosphoglycan from<i>Leishmania donovani</i>is due to an effect on early events in the virus life cycle","year":2001,"lang":"en","type":"article","venue":"Clinical & Experimental Immunology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Centre hospitalier universitaire de Québec","funders":"Canadian Institutes of Health Research; Faculté de Médecine, Université Laval; Université Laval","keywords":"Syncytium; Lipophosphoglycan; Biology; Viral replication; Viral entry; Virology; Virus; Cell culture; Cell biology; Luciferase; Transfection; Immunology; Leishmania donovani; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0007381883,0.0002154772,0.0003969515,0.00007900845,0.0001935227,0.00001603964,0.0003190457,0.00030868,0.0001867416],"category_scores_gemma":[0.0002704597,0.0001384629,0.00009126408,0.0001994881,0.0003524016,0.0001727897,0.0001312069,0.0004530344,0.0009135616],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008728482,"about_ca_system_score_gemma":0.00002912434,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002807472,"about_ca_topic_score_gemma":0.0001796702,"domain_scores_codex":[0.9971226,0.0012614,0.000679973,0.0004895548,0.00008591852,0.0003604868],"domain_scores_gemma":[0.9980769,0.0009020705,0.0002020514,0.0007260873,0.00003692419,0.00005596431],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004692462,0.002171547,0.01064535,0.000003407481,0.0002011215,0.00001527943,0.002613319,7.309025e-7,0.9620115,0.00005521931,0.002002887,0.01558716],"study_design_scores_gemma":[0.006122441,0.009630786,0.2685968,0.00004446288,0.00003364325,0.0000465916,0.0008261689,0.0000114457,0.7090894,0.0001122656,0.005274507,0.000211444],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946533,0.002674644,0.00002161772,0.0009992108,0.0002142454,0.001043302,0.0002509991,0.00003049162,0.000112222],"genre_scores_gemma":[0.9968301,0.000333608,0.00001073105,0.001378874,0.0000286549,0.0003121998,0.00104601,0.00001657618,0.00004325488],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2579515,"threshold_uncertainty_score":0.9998643,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02171268395909641,"score_gpt":0.3295676047016075,"score_spread":0.307854920742511,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}