{"id":"W2136308095","doi":"10.1084/jem.192.8.1081","title":"Apoptosis Control in Syncytia Induced by the HIV Type 1–Envelope Glycoprotein Complex","year":2000,"lang":"en","type":"article","venue":"The Journal of Experimental Medicine","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":218,"is_retracted":false,"has_abstract":true,"ca_institutions":"Amgen (Canada); University of Toronto; Ontario Institute for Cancer Research","funders":"National Institute of General Medical Sciences; National Cancer Institute","keywords":"Syncytium; Cytochrome c; Apoptosis; Cell biology; Biology; Apoptosis-inducing factor; Molecular biology; Inhibitor of apoptosis domain; Mitochondrion; Mitochondrial apoptosis-induced channel; Caspase; Sendai virus; Lamin; Programmed cell death; Virology; Biochemistry; Virus; Nucleus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003997904,0.00009992234,0.0001532388,0.00002267769,0.00006690921,0.000005057935,0.0002053149,0.0000565094,0.000606762],"category_scores_gemma":[0.00001710038,0.00004782964,0.00003476834,0.00008163588,0.0000868408,0.000003810563,0.00001801502,0.0001137079,0.000007482297],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002194352,"about_ca_system_score_gemma":0.00002238521,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005280174,"about_ca_topic_score_gemma":0.000003021321,"domain_scores_codex":[0.9992285,0.0001155301,0.0002826905,0.00007362037,0.0001785686,0.0001210554],"domain_scores_gemma":[0.9996235,0.00001767625,0.0001219039,0.0001529899,0.00003844551,0.00004550222],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005479879,0.00004854895,0.00002075686,0.000001242672,0.00002887113,9.693653e-7,0.0002582523,0.00002218703,0.9916076,0.00001218448,0.004630772,0.002820606],"study_design_scores_gemma":[0.003136065,0.001611435,0.0008150752,0.00005596653,0.00003482688,0.000109146,0.0009447259,0.0001542196,0.9744823,0.00003674804,0.01852078,0.00009873222],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9918344,0.004642054,0.0001393615,0.002274512,0.0001394814,0.000186032,0.000001709133,0.000001649739,0.0007807996],"genre_scores_gemma":[0.9980137,0.000345805,0.00004101089,0.0008543346,0.0002862843,0.000002731977,0.0000122461,0.00001034387,0.0004335471],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01712534,"threshold_uncertainty_score":0.6643618,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01515325931340054,"score_gpt":0.2698569696351487,"score_spread":0.2547037103217482,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}