{"id":"W2136309000","doi":"10.1161/circep.109.933036","title":"Multiple Potential Molecular Contributors to Atrial Hypocontractility Caused by Atrial Tachycardia Remodeling in Dogs","year":2010,"lang":"en","type":"article","venue":"Circulation Arrhythmia and Electrophysiology","topic":"Atrial Fibrillation Management and Outcomes","field":"Medicine","cited_by":121,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Bundesministerium für Bildung und Forschung; Institut de Cardiologie de Montréal; Fondation Leducq; Université de Montréal; Chang Gung Medical Foundation; Deutsche Forschungsgemeinschaft; Canadian Institutes of Health Research; Deutsche Gesellschaft für Kardiologie-Herz und Kreislaufforschung.; Mitacs; Heart and Stroke Foundation of Canada","keywords":"Contractility; Internal medicine; Myosin light-chain kinase; Endocrinology; Protein kinase A; Medicine; Cell biology; Chemistry; Myosin; Kinase; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002785788,0.0002090762,0.0005352495,0.0001914605,0.0001114302,0.00003018911,0.00004794212,0.0002591457,0.00004730103],"category_scores_gemma":[0.0006219448,0.0002052137,0.0002848355,0.0002415171,0.00005066263,0.000113686,0.00003685606,0.0003445284,0.00002203358],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006845513,"about_ca_system_score_gemma":0.00006871434,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001306569,"about_ca_topic_score_gemma":0.00002862537,"domain_scores_codex":[0.9983227,0.0001266079,0.00047053,0.0004779845,0.0001891587,0.0004130481],"domain_scores_gemma":[0.9991981,0.0001418501,0.0001263274,0.0002523579,0.0001064591,0.0001749202],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001717697,0.000004708877,0.02388219,0.00001235211,0.00008777223,0.00003964765,0.00004025368,0.005426469,0.9620975,0.0004987324,0.00004296561,0.00614967],"study_design_scores_gemma":[0.02349459,0.0006249797,0.8311338,0.000021316,0.0005344856,0.0001119713,0.00003646524,0.1152935,0.00935898,0.003221249,0.01524797,0.0009206838],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9909309,0.0001298331,0.004728883,0.002262417,0.0007990003,0.00102182,0.00001040499,0.00006902896,0.00004769313],"genre_scores_gemma":[0.9966566,0.00002512846,0.0003352944,0.000246122,0.002507081,0.000004641392,0.0001592182,0.00002310754,0.00004283004],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9527386,"threshold_uncertainty_score":0.836837,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01137158140019831,"score_gpt":0.274358991364811,"score_spread":0.2629874099646127,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}