{"id":"W2136376873","doi":"10.1038/ng.2554","title":"Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia","year":2013,"lang":"en","type":"review","venue":"Nature Genetics","topic":"Ophthalmology and Visual Impairment Studies","field":"Medicine","cited_by":486,"is_retracted":false,"has_abstract":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"National Center for Advancing Translational Sciences; Wellcome Trust; National Eye Institute; National Institutes of Health; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; National Institute for Health and Care Research","keywords":"Refractive error; Genome-wide association study; Meta-analysis; Biology; 1000 Genomes Project; Single-nucleotide polymorphism; Genetics; Genetic association; Bioinformatics; Medicine; Eye disease; Gene; Genotype; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002876891,0.00159128,0.004732186,0.002248223,0.0002032106,0.0009477572,0.001272145,0.001034443,0.002209513],"category_scores_gemma":[0.005598392,0.0005309674,0.006208349,0.003237143,0.0002485991,0.0005991928,0.0008158035,0.001048691,0.0002389499],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005459001,"about_ca_system_score_gemma":0.001353272,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003385298,"about_ca_topic_score_gemma":0.009572682,"domain_scores_codex":[0.9990184,0.0003451973,0.0002059854,0.000215409,0.0001627938,0.00005216379],"domain_scores_gemma":[0.9965883,0.002652909,0.0003840415,0.000106954,0.0002130652,0.00005464082],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.002750242,0.00009380449,0.02907299,0.1756918,0.2512028,0.0009669134,0.0002143842,0.001272364,0.00158428,0.001345312,0.0125286,0.5232766],"study_design_scores_gemma":[0.00135109,0.0006989519,0.09467187,0.03890504,0.7410055,0.003070288,0.0003394684,0.0006118812,0.001312727,0.005866781,0.1119557,0.0002107048],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001601873,0.997509,0.0002540617,0.0002346169,0.00006721495,0.000008743124,0.0001738177,0.000007920336,0.0001426223],"genre_scores_gemma":[0.02491512,0.9730166,0.000894983,0.0004130885,0.0001649522,0.00002585673,0.0003832264,0.000006111556,0.0001800298],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004732186,"threshold_uncertainty_score":0.01521462,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2434122448984447,"score_gpt":0.502808177774235,"score_spread":0.2593959328757903,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}