{"id":"W2136380020","doi":"10.1128/aem.69.3.1347-1351.2003","title":"Biotransformation of Hexahydro-1,3,5-Trinitro-1,3,5-Triazine (RDX) by a Rabbit Liver Cytochrome P450: Insight into the Mechanism of RDX Biodegradation by <i>Rhodococcus</i> sp. Strain DN22","year":2003,"lang":"en","type":"article","venue":"Applied and Environmental Microbiology","topic":"Chemical Reactions and Isotopes","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":102,"is_retracted":false,"has_abstract":true,"ca_institutions":"Biotechnology Research Institute","funders":"","keywords":"Biotransformation; Metabolite; Rhodococcus; Cytochrome; Chemistry; Cytochrome P450; Strain (injury); Biodegradation; Stereochemistry; Biochemistry; Enzyme; Organic chemistry; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001649822,0.0004520392,0.0002491893,0.00009276672,0.00007445391,0.0001841517,0.0001615156,0.0002590219,0.0002794261],"category_scores_gemma":[0.0001347618,0.0001279375,0.0002580207,0.000108228,0.0001499941,0.0001680997,0.0001596584,0.0002102039,0.0002041144],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002747867,"about_ca_system_score_gemma":0.0002312181,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00208484,"about_ca_topic_score_gemma":0.00201699,"domain_scores_codex":[0.999853,0.00003197612,0.00001027563,0.00003409304,0.00003998074,0.00003074893],"domain_scores_gemma":[0.9999299,0.000007955938,0.00002540552,0.000008975967,0.00001329465,0.00001437265],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003021901,0.00000655897,0.0003002019,0.000007905934,0.000002964881,0.00003287216,0.000009347664,0.00003793867,0.9991461,0.00001331071,0.000002972899,0.0004094674],"study_design_scores_gemma":[0.000004027738,0.0002034335,0.004063029,0.000001303314,0.00001118816,0.0001630394,0.00002537187,0.0005059427,0.9947264,0.00001243617,0.000281008,0.000002834965],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975309,0.0004227524,0.001575469,0.00003517711,0.000003954222,0.00001205654,0.00006469488,0.00001413038,0.0003408826],"genre_scores_gemma":[0.9952532,0.0005578954,0.00297681,0.00001995945,0.000002886214,0.00001081068,0.0002096584,0.00000857796,0.0009601346],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00208484,"threshold_uncertainty_score":0.004145443,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01836805969681877,"score_gpt":0.2709627064048468,"score_spread":0.2525946467080281,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}