{"id":"W2136386001","doi":"10.1146/annurev-med-062613-093128","title":"Metformin in Cancer Treatment and Prevention","year":2014,"lang":"en","type":"review","venue":"Annual Review of Medicine","topic":"Metabolism, Diabetes, and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":485,"is_retracted":false,"has_abstract":true,"ca_institutions":"Population Health Research Institute","funders":"","keywords":"Metformin; Medicine; Cancer; Diabetes mellitus; Type 2 Diabetes Mellitus; Pharmacology; Oncology; Internal medicine; Bioinformatics; Endocrinology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006534078,0.000283622,0.001958308,0.00006755037,0.00001075988,0.000001278623,0.0001262209,0.0001634635,0.0001095843],"category_scores_gemma":[0.0001768611,0.0001718524,0.0002082326,0.0001277863,0.0001006291,0.000002536085,0.00004070633,0.0000765873,0.000002728313],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002863031,"about_ca_system_score_gemma":0.0001847711,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007717981,"about_ca_topic_score_gemma":0.000061423,"domain_scores_codex":[0.9984927,0.0002029039,0.0006889279,0.0003255874,0.0001240714,0.000165764],"domain_scores_gemma":[0.9991125,0.00002480576,0.0004033162,0.0003170376,0.00006973744,0.00007257857],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000002335791,0.00001834485,0.000001186575,0.06885806,0.00008030947,5.134558e-7,0.00001343902,1.056818e-8,0.000001440653,0.00002122792,0.003759326,0.9272438],"study_design_scores_gemma":[0.0003781285,0.0004284908,0.000001435324,0.1220228,0.0008638105,0.00000622338,0.000007496069,5.605085e-8,0.0000139509,0.00001475467,0.8761362,0.0001266661],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00001074495,0.9986499,0.000006702903,0.00003630511,0.0001702513,0.0007160691,0.00005477482,0.0000020558,0.0003531897],"genre_scores_gemma":[0.000001125551,0.9978331,0.00003022009,0.0003705502,0.0005694428,0.0003007952,0.0003188801,0.00002258981,0.0005532545],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9271171,"threshold_uncertainty_score":0.7007939,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03273712840634925,"score_gpt":0.4067972259925361,"score_spread":0.3740600975861869,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}