{"id":"W2136386001","doi":"10.1146/annurev-med-062613-093128","title":"Metformin in Cancer Treatment and Prevention","year":2014,"lang":"en","type":"review","venue":"Annual Review of Medicine","topic":"Metabolism, Diabetes, and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":485,"is_retracted":false,"has_abstract":true,"ca_institutions":"Population Health Research Institute","funders":"","keywords":"Metformin; Medicine; Cancer; Diabetes mellitus; Type 2 Diabetes Mellitus; Pharmacology; Oncology; Internal medicine; Bioinformatics; Endocrinology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006335718,0.0007328336,0.001139676,0.001700855,0.0003385643,0.0009438611,0.0009879039,0.001423103,0.004788161],"category_scores_gemma":[0.0009530826,0.0002110458,0.0005048337,0.001356939,0.0004376528,0.001008908,0.0009011981,0.002706979,0.002329204],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006843321,"about_ca_system_score_gemma":0.001024902,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001016678,"about_ca_topic_score_gemma":0.001885007,"domain_scores_codex":[0.999733,0.00006985745,0.00003344996,0.00003654993,0.0001020941,0.00002495179],"domain_scores_gemma":[0.9997565,0.0001083267,0.00003857559,0.0000110219,0.00005410988,0.00003139106],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005894338,0.00007167293,0.0001251527,0.006310747,0.00007349151,0.0001560422,0.0000448994,0.0002083844,0.0005367939,0.005697866,0.05105598,0.9356601],"study_design_scores_gemma":[0.00002137886,0.00005471256,0.0004474933,0.003321901,0.00005013606,0.0006997286,0.00002567167,0.00005098079,0.000159032,0.002789198,0.9923686,0.00001107992],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00006664623,0.997666,0.0000782126,0.000543276,0.0004241111,0.000004760923,0.00001257478,0.00000785756,0.001196569],"genre_scores_gemma":[0.0007020024,0.9973235,0.0001976156,0.0004776649,0.0004716488,0.000008916953,0.00002417814,0.000001728917,0.0007929042],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004788161,"threshold_uncertainty_score":0.01601797,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03273712840634925,"score_gpt":0.4067972259925361,"score_spread":0.3740600975861869,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}