{"id":"W2136396870","doi":"10.1186/s13063-014-0526-8","title":"Specifying the target difference in the primary outcome for a randomised controlled trial: guidance for researchers","year":2015,"lang":"en","type":"article","venue":"Trials","topic":"Meta-analysis and systematic reviews","field":"Decision Sciences","cited_by":67,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital","funders":"Medical Research Council; Chief Scientist Office, Scottish Government Health and Social Care Directorate; National Institute for Health and Care Research; Cancer Research UK; University of Aberdeen; Scottish Government","keywords":"Medicine; Outcome (game theory); Randomized controlled trial; Alternative medicine; Physical therapy; Internal medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","scholarly_communication"],"consensus_categories":["metaresearch"],"category_scores_codex":[0.764893,0.0002598555,0.008017251,0.0002044215,0.0001895445,0.001149065,0.003255752,0.00008452099,0.0003732746],"category_scores_gemma":[0.7393786,0.00007277845,0.003875673,0.0007618601,0.00008513125,0.0001142597,0.00007369843,0.0001526281,0.0001288896],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005989437,"about_ca_system_score_gemma":0.0002425157,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008175158,"about_ca_topic_score_gemma":0.00001180107,"domain_scores_codex":[0.8737925,0.09406482,0.02360976,0.001066189,0.006832489,0.0006342343],"domain_scores_gemma":[0.5064576,0.4729275,0.01256476,0.005627535,0.002185184,0.0002375457],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.6294771,0.0002420633,0.001275463,0.0001102709,0.0007238839,0.00000247788,0.004369557,0.0001530644,0.0002003351,0.007540082,0.3449835,0.01092213],"study_design_scores_gemma":[0.8078032,0.0002136593,0.0004276901,0.00002607707,0.0003835201,9.03902e-7,0.001621974,0.003437816,0.000015052,0.07614519,0.1097594,0.000165533],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.08931287,0.01601366,0.4743219,0.05634012,0.00479572,0.3333002,0.0001973062,0.00003016174,0.02568802],"genre_scores_gemma":[0.722308,0.0001200376,0.05655889,0.008093941,0.004627607,0.088461,0.00004384148,0.0001012393,0.1196855],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.6329951,"threshold_uncertainty_score":0.9998878,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.9581313989659439,"score_gpt":0.6472956805131397,"score_spread":0.3108357184528042,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}