{"id":"W2136437831","doi":"10.1084/jem.20031237","title":"Toll-like Receptors Induce a Phagocytic Gene Program through p38","year":2003,"lang":"en","type":"article","venue":"The Journal of Experimental Medicine","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":433,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network","funders":"National Institute of Allergy and Infectious Diseases; National Center for Research Resources; National Institute of General Medical Sciences; National Cancer Institute; National Institutes of Health; Canadian Institutes of Health Research; Leukemia and Lymphoma Society; Stop Cancer; U.S. Public Health Service; U.S. Department of Defense","keywords":"Phagocytosis; Biology; Cell biology; Innate immune system; Receptor; TLR2; Microbiology; TLR9; Toll-like receptor; Signal transduction; Macrophage; Scavenger receptor; Immune system; TLR4; Immunology; Gene; Gene expression; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000832303,0.0001492157,0.0002991325,0.00007392667,0.0001589129,0.000005010888,0.0002242824,0.000103705,0.001256109],"category_scores_gemma":[0.00014575,0.00008191096,0.00007271651,0.000141513,0.0003151293,0.0001628256,0.00002421567,0.0003288867,0.0001025075],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009004529,"about_ca_system_score_gemma":0.00007664565,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002227481,"about_ca_topic_score_gemma":4.399677e-7,"domain_scores_codex":[0.9985505,0.0005274562,0.0005228249,0.00007844697,0.00009215233,0.0002285693],"domain_scores_gemma":[0.9992172,0.0001445044,0.0003498839,0.0001904073,0.00007528355,0.00002278342],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006280942,0.0001809339,0.0000152701,0.000002980247,0.0001582914,0.000009728784,0.005628934,0.000001273616,0.9819098,0.0002982114,0.009026211,0.002140315],"study_design_scores_gemma":[0.002493462,0.002165724,0.00006599123,0.0000777655,0.00006903294,0.001826653,0.005803724,4.884658e-7,0.8643156,0.00007555461,0.1230252,0.00008081141],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9549676,0.03802866,0.00007815802,0.0007431593,0.003111535,0.0002698279,2.219153e-7,0.00001931312,0.002781477],"genre_scores_gemma":[0.9973361,0.0005446139,0.0002162293,0.000391187,0.000128617,0.000008217499,0.000005147921,0.00001363084,0.001356248],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1175942,"threshold_uncertainty_score":0.9996569,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02474793688489882,"score_gpt":0.3093915593644403,"score_spread":0.2846436224795414,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}