{"id":"W2136437831","doi":"10.1084/jem.20031237","title":"Toll-like Receptors Induce a Phagocytic Gene Program through p38","year":2003,"lang":"en","type":"article","venue":"The Journal of Experimental Medicine","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":433,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network","funders":"National Institute of Allergy and Infectious Diseases; National Center for Research Resources; National Institute of General Medical Sciences; National Cancer Institute; National Institutes of Health; Canadian Institutes of Health Research; Leukemia and Lymphoma Society; Stop Cancer; U.S. Public Health Service; U.S. Department of Defense","keywords":"Phagocytosis; Biology; Cell biology; Innate immune system; Receptor; TLR2; Microbiology; TLR9; Toll-like receptor; Signal transduction; Macrophage; Scavenger receptor; Immune system; TLR4; Immunology; Gene; Gene expression; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001631746,0.0002427672,0.000124585,0.000207042,0.0001295512,0.000184916,0.00007276581,0.0001394757,0.002243413],"category_scores_gemma":[0.0001751512,0.0001098234,0.0002126628,0.00008075143,0.0001939925,0.0001447275,0.0002963795,0.000341732,0.0005909069],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001417493,"about_ca_system_score_gemma":0.0001366229,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009589095,"about_ca_topic_score_gemma":0.000132355,"domain_scores_codex":[0.9998587,0.00003011347,0.000009582182,0.00002167063,0.00003398902,0.00004593464],"domain_scores_gemma":[0.9998866,0.00002455694,0.00003069023,0.00001837963,0.00001539063,0.00002441591],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002477395,0.00004667644,0.0005267541,0.00005944215,0.000003530041,0.0001265939,0.00002992316,0.00003745282,0.993411,0.0002069425,0.0001012737,0.005202563],"study_design_scores_gemma":[0.00006533452,0.0009234497,0.01539972,0.00001405703,0.00001178211,0.001452022,0.0000799293,0.0008269736,0.9750519,0.0004094664,0.005760725,0.000004589155],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9887859,0.002388258,0.004632096,0.0002496698,0.0000338173,0.00005597097,0.0002670037,0.0001186072,0.003468638],"genre_scores_gemma":[0.9931384,0.0007765925,0.003048232,0.00004811497,0.00001674614,0.00003947244,0.0001960218,0.000008115723,0.002728274],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002243413,"threshold_uncertainty_score":0.00750494,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02474793688489882,"score_gpt":0.3093915593644403,"score_spread":0.2846436224795414,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}