{"id":"W2136442634","doi":"10.1242/jeb.099127","title":"The role of titin in eccentric muscle contraction","year":2014,"lang":"en","type":"article","venue":"Journal of Experimental Biology","topic":"Cardiomyopathy and Myosin Studies","field":"Medicine","cited_by":119,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Killam Trusts","keywords":"Titin; Sarcomere; Myofilament; Isometric exercise; Muscle contraction; Actin; Myosin; Biophysics; Protein filament; Myofibril; Contraction (grammar); Muscle stiffness; Skeletal muscle; Chemistry; Myosin head; Obscurin; Nebulin; Eccentric; Anatomy; Stiffness; Myocyte; Materials science; Myosin light-chain kinase; Biology; Physics; Cell biology; Medicine; Internal medicine; Biochemistry; Physiology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006139138,0.0001618715,0.0001891602,0.0003300218,0.0004411135,0.0003262699,0.0003878143,0.0005223697,0.0005218777],"category_scores_gemma":[0.000399066,0.00008003868,0.0001324649,0.0001497163,0.001165918,0.0005132951,0.0004278043,0.0004300261,0.0001209162],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002376273,"about_ca_system_score_gemma":0.0002724745,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004601701,"about_ca_topic_score_gemma":0.0004200856,"domain_scores_codex":[0.9999015,0.00002808097,0.00000638387,0.00002226061,0.00002255427,0.00001909823],"domain_scores_gemma":[0.9998468,0.00005967687,0.00002837923,0.00001823556,0.00001510737,0.00003169901],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007666342,0.0001921506,0.01977625,0.0008383393,0.0000335297,0.003172543,0.002396175,0.001255995,0.8268008,0.07423375,0.001064489,0.06946931],"study_design_scores_gemma":[0.000145641,0.005446095,0.4537755,0.0008063085,0.0002750381,0.02318528,0.003810499,0.01377631,0.3151678,0.09890678,0.08456308,0.0001415864],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8957801,0.05736467,0.02220489,0.004010733,0.000365848,0.00003937507,0.00003895102,0.00008416551,0.02011125],"genre_scores_gemma":[0.9866602,0.008182969,0.00221557,0.0001852885,0.000133334,0.00001252138,0.00001084312,0.000006578715,0.002592566],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006139138,"threshold_uncertainty_score":0.003246725,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009240045747256344,"score_gpt":0.2902933959607851,"score_spread":0.2810533502135287,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}