{"id":"W2136453695","doi":"10.1677/erc.1.01033","title":"Mechanism of gonadotropin-releasing hormone (GnRH)-I and -II-induced cell growth inhibition in ovarian cancer cells: role of the GnRH-I receptor and protein kinase C pathway","year":2006,"lang":"en","type":"article","venue":"Endocrine Related Cancer","topic":"Hypothalamic control of reproductive hormones","field":"Medicine","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"Child and Family Research Institute; University of British Columbia; BC Children's Hospital","funders":"Canadian Institutes of Health Research; Michael Smith Health Research BC","keywords":"Protein kinase C; Endocrinology; MAPK/ERK pathway; Internal medicine; Ovarian cancer; Gonadotropin-releasing hormone receptor; Gonadotropin-releasing hormone; Kinase; Cell growth; Biology; Signal transduction; Protein kinase A; Cancer research; Chemistry; Cell biology; Hormone; Cancer; Medicine; Luteinizing hormone; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001386871,0.0002620653,0.0005216039,0.0001918249,0.00007926256,0.000007676849,0.00006155731,0.0001180524,0.00005354235],"category_scores_gemma":[0.00005901233,0.0002059072,0.0000811573,0.0004234536,0.0001237089,0.0001204845,0.0001078481,0.00041199,0.000001005938],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002113482,"about_ca_system_score_gemma":0.0002059951,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0115596,"about_ca_topic_score_gemma":0.0002272212,"domain_scores_codex":[0.998188,0.0001181873,0.0005650214,0.0004811523,0.0003144251,0.000333277],"domain_scores_gemma":[0.9990209,0.0000314477,0.0003666655,0.0003092678,0.0001986719,0.00007301861],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000280743,0.0001923222,0.001212151,0.0001495839,0.00005255582,0.0000190909,0.0003028489,0.00001851574,0.9930084,0.001509589,0.00004377938,0.003210412],"study_design_scores_gemma":[0.004731273,0.0002927876,0.02908501,0.0004564289,0.0001168714,0.00002870166,0.0001208891,0.0001586626,0.9629056,0.001549881,0.0003581724,0.0001957113],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9810644,0.01509014,0.00001245464,0.001737868,0.0001203393,0.001266086,0.00004473493,0.00002788701,0.000636132],"genre_scores_gemma":[0.9975348,0.00121051,0.0002591507,0.00002541467,0.0001329013,0.0001538676,0.0000074707,0.00004730582,0.0006285916],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0301028,"threshold_uncertainty_score":0.9950225,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005134026798583379,"score_gpt":0.2058889019849654,"score_spread":0.200754875186382,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}