{"id":"W2136488776","doi":"10.1128/aem.69.11.6777-6784.2003","title":"Binding of Pediocin PA-1 with Anionic Lipid Induces Model Membrane Destabilization","year":2003,"lang":"en","type":"article","venue":"Applied and Environmental Microbiology","topic":"Probiotics and Fermented Foods","field":"Agricultural and Biological Sciences","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Novalait; Agriculture and Agri-Food Canada; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Dairy Farmers of Canada","keywords":"Bacteriocin; Membrane; Phospholipid; Chemistry; Fourier transform infrared spectroscopy; Infrared spectroscopy; Methylene; Biophysics; Amide; Peptide; Crystallography; POPC; Hydrophobic effect; Stereochemistry; Organic chemistry; Chemical engineering; Antimicrobial; Biochemistry; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001047299,0.0002487324,0.0002801698,0.00008311655,0.0001116759,0.0002020473,0.0002275945,0.0002764495,0.0008544758],"category_scores_gemma":[0.000298643,0.0001081724,0.0001128773,0.0001137122,0.0001658967,0.0001463394,0.0002475159,0.0004425943,0.0002219196],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002472084,"about_ca_system_score_gemma":0.0001037073,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005647896,"about_ca_topic_score_gemma":0.0003193859,"domain_scores_codex":[0.9998317,0.00003981024,0.000007604739,0.00002653457,0.00005232204,0.00004196847],"domain_scores_gemma":[0.9998953,0.00003527358,0.00003014612,0.000006500559,0.00001148639,0.00002131776],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008973511,0.00001373632,0.0000857804,0.00001695469,0.00000295438,0.00003254606,0.000008208153,0.0000545695,0.9993212,0.00002602302,0.00001076348,0.0003375612],"study_design_scores_gemma":[0.000009914877,0.0001627001,0.00163442,0.00000325023,0.000004518974,0.00008566077,0.00001757815,0.001292813,0.9961686,0.00002566544,0.0005918369,0.0000031257],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978648,0.0004030765,0.001060424,0.00003764528,0.000008265706,0.00001363755,0.00005590791,0.00001698653,0.000539369],"genre_scores_gemma":[0.9982014,0.0002390914,0.0007823432,0.00005212038,0.000004876087,0.00001527038,0.0001482238,0.00000729393,0.0005493796],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008544758,"threshold_uncertainty_score":0.00285846,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008297565836933052,"score_gpt":0.1600178166399666,"score_spread":0.1517202508030335,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}