{"id":"W2136512078","doi":"10.1110/ps.036244.108","title":"TonB induces conformational changes in surface‐exposed loops of FhuA, outer membrane receptor of <i>Escherichia coli</i>","year":2008,"lang":"en","type":"article","venue":"Protein Science","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"Bacterial outer membrane; Escherichia coli; Biophysics; Conformational change; Chemistry; Membrane protein; Membrane; Crystallography; Microbiology; Biochemistry; Biology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001156781,0.0002396809,0.0001199198,0.00005680121,0.0001153583,0.0001664154,0.0001600985,0.0001682971,0.001047104],"category_scores_gemma":[0.0002035325,0.0001331023,0.0001261923,0.00005243531,0.0001507802,0.0001129805,0.000144958,0.0002941593,0.000234193],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002779083,"about_ca_system_score_gemma":0.00009527335,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008895696,"about_ca_topic_score_gemma":0.000799352,"domain_scores_codex":[0.9998844,0.0000234479,0.000005132177,0.00001834254,0.00001924762,0.00004948011],"domain_scores_gemma":[0.9998909,0.00003756151,0.00002545604,0.00001097141,0.00001198235,0.0000230036],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001452157,0.00002196606,0.0001926939,0.00001583563,0.000002746448,0.00002157576,0.00001862391,0.00003682231,0.9990977,0.00002231989,0.00003199618,0.0003925345],"study_design_scores_gemma":[0.0000162944,0.0002637486,0.009684963,0.000005124405,0.000007161489,0.0001074875,0.00004657033,0.0009852163,0.9881759,0.00002221851,0.0006802236,0.000005214438],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991733,0.0001004467,0.000251136,0.00002239715,0.000005446631,0.000005040256,0.00003581828,0.00001518898,0.000391202],"genre_scores_gemma":[0.9987438,0.00007902476,0.0003287088,0.00005555883,0.000002696204,0.00000952216,0.0001411503,0.00001034204,0.0006292303],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001047104,"threshold_uncertainty_score":0.003502905,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01757783133521832,"score_gpt":0.2321506766403189,"score_spread":0.2145728453051006,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}