{"id":"W2136542008","doi":"10.1073/pnas.0900596106","title":"Control of p53 multimerization by Ubc13 is JNK-regulated","year":2009,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"National Cancer Institute; U.S. Public Health Service; University of California, San Diego; National Institutes of Health; Leukemia and Lymphoma Society","keywords":"Polysome; Phosphorylation; Suppressor; Regulator; Threonine; Mutant; Ubiquitin; Cell biology; Cytosol; Biology; Kinase; Transcriptional regulation; Ubiquitin-conjugating enzyme; Biochemistry; Translation (biology); Transcription factor; Serine; Chemistry; RNA; Ribosome; Messenger RNA; Ubiquitin ligase; Enzyme; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001535667,0.0003399578,0.0001868693,0.0001716764,0.0003215429,0.000428749,0.0001952081,0.0001568724,0.001279647],"category_scores_gemma":[0.0001206194,0.0001120785,0.0002028618,0.0001883844,0.00026253,0.0001763739,0.0003166017,0.0003839693,0.0005165314],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006794051,"about_ca_system_score_gemma":0.000309564,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008509475,"about_ca_topic_score_gemma":0.001642761,"domain_scores_codex":[0.9998697,0.00001389879,0.00001210541,0.00002884929,0.00003867692,0.0000367315],"domain_scores_gemma":[0.9998692,0.0000086982,0.00003825854,0.00001431546,0.00002776049,0.00004171708],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001573024,0.00001916783,0.0002313038,0.0000282276,0.00000335824,0.00004782519,0.000008042198,0.00005451386,0.9977672,0.0001297517,0.00004728037,0.001505919],"study_design_scores_gemma":[0.00001369428,0.00005163727,0.008704567,0.000004706384,0.00000800796,0.0001919606,0.00002459921,0.001634659,0.987328,0.0001118098,0.001921411,0.000005074499],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9900989,0.002765404,0.00378023,0.0001513865,0.00005453013,0.00003194464,0.0003837891,0.00009125193,0.002642532],"genre_scores_gemma":[0.9935089,0.001124653,0.001754188,0.00003469543,0.000009558722,0.0000260953,0.0003757931,0.00002227375,0.003143824],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001279647,"threshold_uncertainty_score":0.004929423,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01875164778860386,"score_gpt":0.2889698589374365,"score_spread":0.2702182111488327,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}