{"id":"W2136626927","doi":"10.1038/ismej.2008.24","title":"<i>Escherichia coli</i>transcription factor YncC (McbR) regulates colanic acid and biofilm formation by repressing expression of periplasmic protein YbiM (McbA)","year":2008,"lang":"en","type":"article","venue":"The ISME Journal","topic":"Bacterial biofilms and quorum sensing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":90,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics; National Institute of Biomedical Imaging and Bioengineering; National Institutes of Health; Keio University","keywords":"Biology; Biofilm; Repressor; Periplasmic space; Overproduction; Transcription factor; Transcription (linguistics); Quorum sensing; Escherichia coli; Molecular biology; Microbiology; Gene; Biochemistry; Bacteria; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007564088,0.0006041966,0.0002370347,0.0001661465,0.0001312458,0.0002808261,0.0001915454,0.0002137993,0.001512047],"category_scores_gemma":[0.0001255611,0.0001397594,0.0002283305,0.000143291,0.0001677317,0.0001088905,0.0002862724,0.0004314803,0.001032789],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006062436,"about_ca_system_score_gemma":0.0003685568,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003817496,"about_ca_topic_score_gemma":0.005991222,"domain_scores_codex":[0.9998457,0.00001597155,0.00001043445,0.00003613259,0.00005648949,0.00003509423],"domain_scores_gemma":[0.9999063,0.00001093978,0.0000304091,0.000008991622,0.0000153716,0.00002801594],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002104897,0.000004803053,0.00008760124,0.000007555924,7.352581e-7,0.000009039532,0.00000228708,0.00001175452,0.9995862,0.0000166205,0.00003279278,0.0002195459],"study_design_scores_gemma":[0.000008059366,0.00007335236,0.0075776,0.000005625313,0.000004605306,0.0001095827,0.00002022491,0.0009371085,0.9890589,0.00002008226,0.002178479,0.000006394225],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9883856,0.001411516,0.005190953,0.0003035622,0.0000662102,0.00004549892,0.001713943,0.0004791675,0.002403589],"genre_scores_gemma":[0.9851592,0.000424161,0.006079924,0.0001525918,0.00001429528,0.00006512758,0.002770687,0.0001090168,0.00522487],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003817496,"threshold_uncertainty_score":0.007590532,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01171145804580378,"score_gpt":0.2102778034960191,"score_spread":0.1985663454502153,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}