{"id":"W2136655134","doi":"10.1200/jco.2008.18.1024","title":"Breast Cancer Subtypes and Response to Docetaxel in Node-Positive Breast Cancer: Use of an Immunohistochemical Definition in the BCIRG 001 Trial","year":2009,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Breast Cancer Treatment Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":535,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"National Cancer Institute","keywords":"Medicine; Breast cancer; Internal medicine; Docetaxel; Oncology; Immunohistochemistry; Cyclophosphamide; Triple-negative breast cancer; Trastuzumab; Estrogen receptor; Hazard ratio; Population; Cancer; Chemotherapy; Confidence interval","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001552428,0.0001487275,0.0006906039,0.00009174558,0.00003145023,0.0000106604,0.0001886088,0.0002794598,0.00001192439],"category_scores_gemma":[0.0004166115,0.0001035754,0.0001437806,0.000140111,0.0001966845,0.00002246466,0.0000399198,0.0003564403,5.013403e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001561652,"about_ca_system_score_gemma":0.0007130571,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008290632,"about_ca_topic_score_gemma":0.001081582,"domain_scores_codex":[0.9974389,0.0008411023,0.001098925,0.000238924,0.0001780841,0.0002040314],"domain_scores_gemma":[0.9982223,0.0006436627,0.00061196,0.0001733215,0.0002407082,0.0001080607],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.7741026,0.005141432,0.06520399,0.000009743942,0.0002980097,0.0001757515,0.0006884835,0.0001113997,0.03390787,0.00004259111,0.001123597,0.1191946],"study_design_scores_gemma":[0.02826803,0.004500941,0.964934,0.00008097765,0.0001057619,0.0004224149,0.0001214673,0.000005352446,0.000527085,0.00009457708,0.0008205979,0.0001188228],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9864839,0.0006631644,0.000004939232,0.01218848,0.0002396635,0.0002114417,0.0001616096,0.000001357598,0.000045449],"genre_scores_gemma":[0.995557,0.001575277,0.0004017422,0.001929066,0.0004933527,0.00001964557,0.000009023187,0.000008139286,0.000006783801],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.89973,"threshold_uncertainty_score":0.4223683,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06568569234966365,"score_gpt":0.4202505576399727,"score_spread":0.354564865290309,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}