{"id":"W2136655134","doi":"10.1200/jco.2008.18.1024","title":"Breast Cancer Subtypes and Response to Docetaxel in Node-Positive Breast Cancer: Use of an Immunohistochemical Definition in the BCIRG 001 Trial","year":2009,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Breast Cancer Treatment Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":535,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"National Cancer Institute","keywords":"Medicine; Breast cancer; Internal medicine; Docetaxel; Oncology; Immunohistochemistry; Cyclophosphamide; Triple-negative breast cancer; Trastuzumab; Estrogen receptor; Hazard ratio; Population; Cancer; Chemotherapy; Confidence interval","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004199244,0.0005518711,0.0009443536,0.0002532488,0.0002019212,0.0007910738,0.0005275563,0.0007668147,0.0008047344],"category_scores_gemma":[0.003093413,0.0002200526,0.0006167693,0.0003570862,0.0004261938,0.0004182102,0.0002720454,0.001220848,0.0001654722],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007771249,"about_ca_system_score_gemma":0.000615198,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000851691,"about_ca_topic_score_gemma":0.002733133,"domain_scores_codex":[0.9979152,0.001565816,0.00009834712,0.0001400057,0.0001731988,0.0001073385],"domain_scores_gemma":[0.9983991,0.0005704297,0.0005089234,0.000121879,0.00009504718,0.000304569],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.7561201,0.00310637,0.1605961,0.0008132762,0.002578884,0.00007901294,0.000192501,0.001682625,0.005825461,0.0002876003,0.002049646,0.06666844],"study_design_scores_gemma":[0.3154599,0.1286358,0.5309741,0.0004124649,0.005162495,0.0005778757,0.0002007637,0.004925267,0.003839156,0.0007516703,0.008966128,0.00009435837],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936451,0.004296668,0.000113794,0.0002906348,0.00005630538,0.0002016646,0.0002088042,0.000008196422,0.001178984],"genre_scores_gemma":[0.9970495,0.0008515516,0.0002910837,0.0003459495,0.00008379854,0.0001846838,0.0006950347,0.000005696898,0.000492688],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004199244,"threshold_uncertainty_score":0.02220803,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06568569234966365,"score_gpt":0.4202505576399727,"score_spread":0.354564865290309,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}