{"id":"W2136666308","doi":"10.1136/gutjnl-2011-300934","title":"Early use of immunosuppressives or TNF antagonists for the treatment of Crohn's disease: time for a change","year":2011,"lang":"en","type":"review","venue":"Gut","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":122,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Medicine; Azathioprine; Infliximab; Disease; Methotrexate; Inflammatory bowel disease; Crohn's disease; Adverse effect; Surgery; Internal medicine; Gastroenterology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008026601,0.0009941723,0.001625287,0.001663292,0.0002916697,0.0008585844,0.001105155,0.001466331,0.003104076],"category_scores_gemma":[0.001186833,0.0002656993,0.0004949135,0.002143262,0.0006634498,0.001959552,0.0005739111,0.002502218,0.002556726],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007799166,"about_ca_system_score_gemma":0.0009275016,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009087001,"about_ca_topic_score_gemma":0.002032952,"domain_scores_codex":[0.9997342,0.00005541533,0.00004440119,0.00003906601,0.0001058583,0.0000210587],"domain_scores_gemma":[0.9994732,0.0002544719,0.00007550204,0.0000204713,0.0001302371,0.00004611542],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001182562,0.0000567761,0.0001264108,0.009952194,0.00006727273,0.0002075839,0.0000416507,0.0002012133,0.0009188133,0.002424267,0.03714254,0.9487431],"study_design_scores_gemma":[0.00003903828,0.00008117939,0.000767244,0.003493651,0.00008136193,0.001698897,0.00005136078,0.00004766805,0.0002628966,0.001592837,0.9918689,0.00001496244],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00006087404,0.9986691,0.00007499742,0.0003753193,0.0002701533,0.000002214184,0.000006627464,0.000005564229,0.0005351672],"genre_scores_gemma":[0.0004450041,0.9982822,0.0001863699,0.0003161277,0.0002069041,0.000004233848,0.00001484458,0.000001926084,0.0005423017],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003104076,"threshold_uncertainty_score":0.0103842,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.077635247885701,"score_gpt":0.3282532709201023,"score_spread":0.2506180230344013,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}