{"id":"W2136672328","doi":"10.4049/jimmunol.169.5.2736","title":"IL-2 Receptor Blockade Inhibits Late, But Not Early, IFN-γ and CD40 Ligand Expression in Human T Cells: Disruption of Both IL-12-Dependent and -Independent Pathways of IFN-γ Production","year":2002,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":73,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Thomas Hospital","funders":"","keywords":"CD40; Blockade; Cell biology; Receptor; Biology; Chemistry; Cytotoxic T cell; In vitro; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000185239,0.0004783584,0.0004136555,0.0001297257,0.0001149485,0.0003638724,0.0001746909,0.0002997215,0.001336769],"category_scores_gemma":[0.0001480564,0.000137427,0.0002302489,0.0001295433,0.0001669765,0.0001442506,0.0001079396,0.0009217576,0.0005207508],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002064109,"about_ca_system_score_gemma":0.0002892378,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006459927,"about_ca_topic_score_gemma":0.0009377697,"domain_scores_codex":[0.999756,0.00005519186,0.00002864015,0.00003262472,0.0000356527,0.00009187496],"domain_scores_gemma":[0.9999121,0.00002710922,0.00001297946,0.00001654796,0.000008529416,0.00002259472],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003698795,0.0001588193,0.00008709353,0.00003367208,0.00000512214,0.00006073398,0.00002275154,0.0001072309,0.997771,0.00002785443,0.00005681127,0.001299037],"study_design_scores_gemma":[0.00009124825,0.001289218,0.001344731,0.000004422763,0.00001774294,0.0001640759,0.00001211619,0.0006170693,0.9951186,0.00001615723,0.001321676,0.000002975465],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954309,0.001604712,0.00121373,0.0001082099,0.00005888717,0.00004700499,0.0002826527,0.00006960655,0.001184248],"genre_scores_gemma":[0.9942961,0.001024404,0.001357696,0.0001023408,0.00003961899,0.00009026942,0.0006148599,0.00001814464,0.002456462],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001336769,"threshold_uncertainty_score":0.004471958,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01654021432614796,"score_gpt":0.2166573974378204,"score_spread":0.2001171831116724,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}