{"id":"W2136672328","doi":"10.4049/jimmunol.169.5.2736","title":"IL-2 Receptor Blockade Inhibits Late, But Not Early, IFN-γ and CD40 Ligand Expression in Human T Cells: Disruption of Both IL-12-Dependent and -Independent Pathways of IFN-γ Production","year":2002,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":73,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Thomas Hospital","funders":"","keywords":"CD40; Blockade; Cell biology; Receptor; Biology; Chemistry; Cytotoxic T cell; In vitro; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007859885,0.0002007532,0.0004727221,0.0003577102,0.0001579217,0.00001030274,0.0001766635,0.0003170965,0.0002206722],"category_scores_gemma":[0.00009148715,0.000146135,0.0000796162,0.0001079655,0.0003280118,0.0002675193,0.0001266198,0.0007531173,0.00001650902],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006062657,"about_ca_system_score_gemma":0.00001942209,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001537561,"about_ca_topic_score_gemma":0.00003088748,"domain_scores_codex":[0.9979846,0.0005540494,0.000928087,0.0001972413,0.00009311351,0.0002429297],"domain_scores_gemma":[0.9984152,0.000125019,0.00103374,0.0002447386,0.0001616438,0.0000197041],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001269946,0.0003113786,0.0006234435,0.00003118824,0.0001306749,0.000002554453,0.003483152,0.00002540524,0.9910963,0.00001550739,0.0003939656,0.002616522],"study_design_scores_gemma":[0.002091557,0.001479523,0.0188672,0.0002082553,0.00006767821,0.0005036165,0.001394227,0.000005045393,0.9744146,0.00003367562,0.0008067336,0.000127883],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9925666,0.004823867,0.00003738379,0.0001878699,0.002019566,0.0002223073,0.000007656526,0.00001074442,0.0001239904],"genre_scores_gemma":[0.9921734,0.005346034,0.00002221469,0.00001965833,0.00005064761,0.00000366636,0.000005099873,0.00001733577,0.002361901],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01824376,"threshold_uncertainty_score":0.5959214,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01654021432614796,"score_gpt":0.2166573974378204,"score_spread":0.2001171831116724,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}