{"id":"W2136718845","doi":"10.1074/jbc.m213182200","title":"Different Properties of SEK1 and MKK7 in Dual Phosphorylation of Stress-induced Activated Protein Kinase SAPK/JNK in Embryonic Stem Cells","year":2003,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Melanoma and MAPK Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":72,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; University of Toronto","funders":"Japan Society for the Promotion of Science; Mitsubishi Foundation; Ministry of Education, Culture, Sports, Science and Technology","keywords":"Embryonic stem cell; Cell biology; Phosphorylation; Protein kinase A; Dual (grammatical number); Kinase; Chemistry; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002143215,0.0001426541,0.0003264559,0.00003172252,0.00001155125,0.000005135351,0.00008166528,0.0002669413,0.00001281611],"category_scores_gemma":[0.00009334829,0.00009577731,0.00007209784,0.00007245588,0.00006906024,0.000005079097,0.000043501,0.0001886635,1.039293e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002324767,"about_ca_system_score_gemma":0.00007296909,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004544324,"about_ca_topic_score_gemma":0.000002421325,"domain_scores_codex":[0.9989878,0.00009544866,0.0004823954,0.0001688205,0.0001103482,0.0001551693],"domain_scores_gemma":[0.9993604,0.00001344806,0.0003637353,0.0001183656,0.00008077229,0.00006326624],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003924821,0.0002591561,0.00937957,0.0001435321,0.00002021352,0.00001585522,0.00004448207,0.00001009965,0.9893628,0.000007515426,0.00000275535,0.0003615321],"study_design_scores_gemma":[0.000937417,0.0005288848,0.00576552,0.0001869055,0.00000604267,0.00002085696,0.0001861843,0.000005075063,0.9921906,0.00003248949,0.00003279476,0.0001072435],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988407,0.0008382237,0.000005671933,0.00001557398,0.00002721185,0.0001343703,0.000008207686,0.000001478527,0.0001285846],"genre_scores_gemma":[0.9997114,0.0001456982,0.00004384615,0.000005209493,0.00002975677,0.00000531227,0.00000502887,0.000006165688,0.00004758611],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00361405,"threshold_uncertainty_score":0.3905685,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02484527172999496,"score_gpt":0.2171518633859983,"score_spread":0.1923065916560034,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}