{"id":"W2136760924","doi":"10.1128/aac.01681-09","title":"Prophylactic Activity of Intramuscular Peramivir in Mice Infected with a Recombinant Influenza A/WSN/33 (H1N1) Virus Containing the H274Y Neuraminidase Mutation","year":2010,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Influenza Virus Research Studies","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Centre hospitalier de l'Université Laval","funders":"BioCryst","keywords":"Oseltamivir; Neuraminidase; Medicine; Regimen; Neuraminidase inhibitor; Virus; Weight loss; Internal medicine; Virology; Gastroenterology; Pharmacology; Coronavirus disease 2019 (COVID-19)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003761114,0.0006741455,0.0008219813,0.0005623724,0.0002154055,0.0002819222,0.0004902149,0.0005617188,0.0009552786],"category_scores_gemma":[0.0002215862,0.0002373375,0.0003780487,0.0002447956,0.0003907787,0.0003816097,0.0001430179,0.001398148,0.0001872306],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003007299,"about_ca_system_score_gemma":0.0004786439,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009250248,"about_ca_topic_score_gemma":0.001387785,"domain_scores_codex":[0.9997578,0.00005437408,0.00001859253,0.00004458104,0.00004110869,0.00008354068],"domain_scores_gemma":[0.9997004,0.00005320986,0.00008191461,0.00003158484,0.00002819302,0.0001046984],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004188515,0.002305384,0.0005442362,0.0001437766,0.0000356783,0.00007089823,0.000066665,0.0004036704,0.9823759,0.0001484331,0.0001721008,0.009544737],"study_design_scores_gemma":[0.000554685,0.06450251,0.005595305,0.00003318539,0.0001059161,0.0002440364,0.00006726423,0.002281932,0.9253679,0.00009677832,0.001131269,0.00001930526],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965216,0.001130244,0.0008478538,0.0001102525,0.00007919664,0.00009721697,0.000237699,0.00009755884,0.0008784154],"genre_scores_gemma":[0.9947894,0.001148228,0.002041488,0.00006830966,0.00004280233,0.0001145206,0.0002970957,0.0000140222,0.001484269],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009552786,"threshold_uncertainty_score":0.003195763,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02651651025312579,"score_gpt":0.3187937224338284,"score_spread":0.2922772121807026,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}