{"id":"W2136773734","doi":"10.1042/bj20140208","title":"Exploring the roles of PALB2 at the crossroads of DNA repair and cancer","year":2014,"lang":"en","type":"review","venue":"Biochemical Journal","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research","keywords":"PALB2; Homologous recombination; DNA repair; BRCA2 Protein; Genetics; Breast cancer; DNA damage; Cancer research; Cancer; Biology; Mutation; Genome instability; Medicine; DNA; Germline mutation; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002814762,0.0005146411,0.0007795358,0.001879785,0.0002538278,0.0006940518,0.0006131755,0.0008950918,0.003724342],"category_scores_gemma":[0.0003199906,0.0002380369,0.0002907418,0.001611677,0.000352879,0.00114768,0.000496478,0.001208955,0.002255474],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005774439,"about_ca_system_score_gemma":0.0006949618,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007409863,"about_ca_topic_score_gemma":0.00136855,"domain_scores_codex":[0.9999145,0.00001140879,0.00001092633,0.00001782094,0.0000334612,0.00001174576],"domain_scores_gemma":[0.9998761,0.00003971941,0.00001773626,0.000004478377,0.00004270945,0.00001926123],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001176239,0.00006144926,0.0002495863,0.01422678,0.00007429215,0.0004085317,0.0000679632,0.0003530897,0.008097506,0.004984898,0.02314116,0.948217],"study_design_scores_gemma":[0.0000118154,0.00007437987,0.0008330851,0.001429983,0.00006087568,0.001551202,0.0000546973,0.00007295857,0.001446319,0.001866982,0.992583,0.0000145647],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000233936,0.9977323,0.0001778365,0.0003294631,0.0001561611,0.000003459507,0.00001638477,0.000007543112,0.001342994],"genre_scores_gemma":[0.001044036,0.9972515,0.0002547797,0.0001738231,0.000125463,0.000004462211,0.00003519998,0.000001814148,0.001108933],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003724342,"threshold_uncertainty_score":0.01245916,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05284963489599379,"score_gpt":0.3145091090102,"score_spread":0.2616594741142062,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}