{"id":"W2136802649","doi":"10.1113/jphysiol.2012.235382","title":"Role of the Wnt‐Frizzled system in cardiac pathophysiology: a rapidly developing, poorly understood area with enormous potential","year":2012,"lang":"en","type":"review","venue":"The Journal of Physiology","topic":"Wnt/β-catenin signaling in development and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":148,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Montreal Heart Institute; McGill University; Bell (Canada)","funders":"Canadian Institutes of Health Research; Fondation Leducq; Heart and Stroke Foundation of Canada","keywords":"Frizzled; Wnt signaling pathway; Pathophysiology; Neuroscience; Biology; Medicine; Bioinformatics; Cell biology; Signal transduction; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007510951,0.0004143152,0.001505027,0.0001084074,0.00009344237,0.000007173683,0.0009846741,0.000424898,0.000008875108],"category_scores_gemma":[0.00002220533,0.0001992798,0.0005548086,0.0002084755,0.000275743,0.000006809893,0.0002550455,0.0005136235,0.000003914201],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001143129,"about_ca_system_score_gemma":0.0009806679,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000180182,"about_ca_topic_score_gemma":0.00001035254,"domain_scores_codex":[0.9972527,0.001014611,0.0008621244,0.0002344547,0.0002259694,0.00041012],"domain_scores_gemma":[0.9976368,0.00007250658,0.001592207,0.0004391906,0.0002038479,0.00005545273],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001571709,0.0002447095,0.00007960635,0.007177914,0.004833665,0.00001416565,0.0009843194,0.0003683786,0.8758256,0.0002592386,0.0008513937,0.1077892],"study_design_scores_gemma":[0.005889762,0.004239032,0.004712351,0.02641697,0.01262669,0.001896545,0.004566448,0.00001433153,0.06861851,0.001898019,0.8651948,0.003926524],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.04527248,0.9535328,0.00005370441,0.00002434596,0.0006153693,0.000403798,0.00001654825,0.000004070263,0.00007695826],"genre_scores_gemma":[0.2589076,0.7401236,0.0001193826,0.00004838211,0.0006265091,0.00002427796,0.00003017543,0.00005076546,0.00006927049],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8643434,"threshold_uncertainty_score":0.8126394,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01415847363315309,"score_gpt":0.2345569375235448,"score_spread":0.2203984638903917,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}