{"id":"W2136874709","doi":"10.2174/157339910793360897","title":"Gene Therapy to Improve Pancreatic Islet Transplantation for Type 1 Diabetes Mellitus","year":2010,"lang":"en","type":"review","venue":"Current Diabetes Reviews","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Genetic enhancement; Transplantation; Medicine; Islet; Viral vector; Pancreatic islets; Immunology; Cancer research; Diabetes mellitus; Biology; Internal medicine; Endocrinology; Gene; Genetics","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001033613,0.001114489,0.005327065,0.000425695,0.0001368012,0.00009141349,0.0003618062,0.0004961526,0.0003787696],"category_scores_gemma":[0.0009879587,0.0007655284,0.001629789,0.000776949,0.00008240606,0.00010919,0.0000356341,0.0007250811,0.001039774],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001376139,"about_ca_system_score_gemma":0.0003309112,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":8.593988e-7,"about_ca_topic_score_gemma":3.129166e-7,"domain_scores_codex":[0.9955564,0.0002956185,0.001758002,0.001076264,0.000358103,0.0009556811],"domain_scores_gemma":[0.9964958,0.0007567952,0.000723263,0.001159069,0.0002787918,0.0005862639],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002043296,0.0001771274,0.00008427733,0.06266006,0.0002328121,6.092998e-7,0.00003316182,3.339292e-8,0.0005129731,0.00001524593,0.006530808,0.9297324],"study_design_scores_gemma":[0.0009417338,0.0006782971,0.00001947511,0.02595985,0.004565324,0.000002289048,0.000001364238,0.00001249779,0.0009461978,0.00004247853,0.9660936,0.0007368924],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001256867,0.9830737,0.00006469637,0.00005751843,0.003896066,0.01082476,0.0004639064,0.0001410704,0.0002214476],"genre_scores_gemma":[0.000004128741,0.9866435,0.001895714,0.0006392054,0.001681108,0.005098485,0.003529742,0.0001799926,0.0003281123],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9595628,"threshold_uncertainty_score":0.999738,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1002287132883027,"score_gpt":0.3819235911452206,"score_spread":0.2816948778569179,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}