{"id":"W2136955543","doi":"10.1073/pnas.1208689109","title":"Physical manipulation of the <i>Escherichia coli</i> chromosome reveals its soft nature","year":2012,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Bacteriophages and microbial interactions","field":"Environmental Science","cited_by":213,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"National Institute of General Medical Sciences","keywords":"Nucleoid; Biophysics; Chromosome; Escherichia coli; Circular bacterial chromosome; Biology; Turgor pressure; Genetics; Chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004397749,0.000072622,0.0001046492,0.00002257371,0.0001746631,0.00001075839,0.0006023556,0.00007746535,0.0001072489],"category_scores_gemma":[0.0001333779,0.00004142008,0.00009015365,0.0005590316,0.0005331919,0.0007485768,0.0002298767,0.0002179289,0.000007327249],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004548117,"about_ca_system_score_gemma":0.000006159755,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008306792,"about_ca_topic_score_gemma":1.338206e-7,"domain_scores_codex":[0.9989218,0.000007651485,0.0002000529,0.0001276346,0.0006048257,0.0001380808],"domain_scores_gemma":[0.9994743,0.00004441491,0.0003954688,0.00001041687,0.00004803311,0.00002730987],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000003457221,0.00006457396,0.007828228,0.0000137251,0.00000434703,3.105375e-10,0.0002056216,0.00005309376,0.9861853,0.004574609,0.001000119,0.00006691483],"study_design_scores_gemma":[0.00003811264,0.000009884129,0.4752097,0.00002950519,0.000008977017,0.000002375662,0.00003614536,0.0001734138,0.5219685,0.001876787,0.0006078465,0.00003865635],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9922705,0.00003681424,3.293323e-7,0.001477042,0.00005917829,0.0001524239,0.00001442919,0.000004439147,0.005984856],"genre_scores_gemma":[0.9988913,0.000004390342,0.0002351353,0.0003784867,0.0001003553,0.000004208786,1.029053e-7,0.000003141086,0.0003829041],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4673815,"threshold_uncertainty_score":0.1964568,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02449075608249986,"score_gpt":0.2883213826792373,"score_spread":0.2638306265967375,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}