{"id":"W2136982714","doi":"10.1016/j.ijpharm.2005.10.008","title":"Interactions of oleic acid and model stratum corneum membranes as seen by 2H NMR","year":2005,"lang":"en","type":"article","venue":"International Journal of Pharmaceutics","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":93,"is_retracted":false,"has_abstract":false,"ca_institutions":"Simon Fraser University; University of British Columbia","funders":"National Research Council Canada; Danmarks Grundforskningsfond","keywords":"Oleic acid; Membrane; Palmitic acid; Chemistry; Stratum corneum; Lamellar structure; Chromatography; Penetration (warfare); Ceramide; Phospholipid; Fatty acid; Crystallography; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001827994,0.0002851814,0.000201385,0.0001932239,0.0004193424,0.0002831835,0.000313059,0.0004672681,0.001911748],"category_scores_gemma":[0.0003172219,0.0001625945,0.0002455588,0.000161674,0.0002307354,0.0004431752,0.000216843,0.000564565,0.0003347697],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002946084,"about_ca_system_score_gemma":0.000212533,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001657438,"about_ca_topic_score_gemma":0.001260727,"domain_scores_codex":[0.9998276,0.00002896618,0.000007409124,0.00003346953,0.00003021103,0.0000723697],"domain_scores_gemma":[0.9998792,0.00005226154,0.00002162,0.00001282893,0.00001713042,0.00001688906],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003508376,0.00002052109,0.00009607908,0.00002353608,0.000009621849,0.00008835566,0.00003301862,0.000110081,0.9984874,0.0001139764,0.00003777806,0.0006288929],"study_design_scores_gemma":[0.00002115329,0.0002458473,0.00249112,0.000008728164,0.00002534254,0.0001041909,0.00007429183,0.001239055,0.9942306,0.0001069449,0.00143894,0.00001374451],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941148,0.001408288,0.001432577,0.000101607,0.00004142928,0.00001315531,0.0001977772,0.00001909714,0.00267134],"genre_scores_gemma":[0.9958999,0.000754058,0.0009789087,0.0000764724,0.00001248732,0.00001351696,0.0002357709,0.00001163409,0.002017279],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001911748,"threshold_uncertainty_score":0.006395459,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08379440374646817,"score_gpt":0.4655005703010683,"score_spread":0.3817061665546001,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}