{"id":"W2136994899","doi":"10.1111/j.1365-2516.2010.02397.x","title":"Immunoglobulin isotypes and functional anti-FVIII antibodies in response to FVIII treatment in Balb/c and C57BL/6 haemophilia A mice","year":2010,"lang":"en","type":"article","venue":"Haemophilia","topic":"Hemophilia Treatment and Research","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"Canadian Institutes of Health Research","keywords":"Antibody; Haemophilia A; BALB/c; Titer; Immunology; Immune system; Haemophilia; Cytokine; Medicine; Molecular biology; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004645924,0.0008518204,0.000451935,0.001792524,0.0002662031,0.0005353959,0.0003881453,0.00110083,0.001779526],"category_scores_gemma":[0.0003706941,0.0003629362,0.0005484968,0.0003832068,0.0005783772,0.000354688,0.0001988922,0.001989245,0.0005588809],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005190431,"about_ca_system_score_gemma":0.0002376992,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001218375,"about_ca_topic_score_gemma":0.001062916,"domain_scores_codex":[0.9993713,0.00008464955,0.00007222722,0.0001768073,0.0001243192,0.000170642],"domain_scores_gemma":[0.9986126,0.000163994,0.000466685,0.0000879375,0.000105528,0.0005632266],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008784214,0.0002740266,0.0003714504,0.00003300126,0.000009822406,0.00008181043,0.00003323771,0.0000481799,0.9975315,0.00005977233,0.00003999885,0.0006386542],"study_design_scores_gemma":[0.0003573761,0.006009109,0.05395927,0.00004531324,0.0001263825,0.001079464,0.0001205836,0.001434278,0.934651,0.000185958,0.001984628,0.00004675106],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950506,0.001293864,0.0008679013,0.0001203258,0.00004734472,0.00005766978,0.001107903,0.0001152854,0.001339142],"genre_scores_gemma":[0.9893641,0.001122166,0.002236886,0.0002461891,0.00005540336,0.0001877184,0.001458204,0.00008312383,0.005246178],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001792524,"threshold_uncertainty_score":0.005953133,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02268019430511863,"score_gpt":0.3023535013869252,"score_spread":0.2796733070818066,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}