{"id":"W2137095509","doi":"10.1534/genetics.114.172874","title":"Mitotic Accumulation of Dimethylated Lysine 79 of Histone H3 Is Important for Maintaining Genome Integrity During Mitosis in Human Cells","year":2014,"lang":"en","type":"article","venue":"Genetics","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Canadian Institutes of Health Research; Research Manitoba; Manitoba Health Research Council","keywords":"Biology; Mitosis; Histone; Cell biology; Histone H2B; Histone H3; Mitotic exit; Genetics; Ubiquitin; Ubiquitin ligase; Cell division; Cell; Spindle apparatus; DNA; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006399095,0.0001661595,0.0001786479,0.0002279163,0.0002800734,0.0002987247,0.0001765528,0.0002681779,0.0009595252],"category_scores_gemma":[0.00007001804,0.000165036,0.000138379,0.0002188816,0.0001656555,0.0001655386,0.0002471028,0.000233237,0.0003364569],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003020174,"about_ca_system_score_gemma":0.0002217999,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001948969,"about_ca_topic_score_gemma":0.002960955,"domain_scores_codex":[0.9999491,0.000002613835,0.000003020471,0.00001811578,0.00001652247,0.00001067064],"domain_scores_gemma":[0.9999626,0.000004101984,0.00001397888,0.000004283987,0.000005863445,0.000009199798],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006461497,0.000005436466,0.0006728413,0.00003139238,0.000003832641,0.00004665965,0.00001616094,0.00005581571,0.996546,0.000123303,0.00004974825,0.002384179],"study_design_scores_gemma":[0.00001148337,0.0001053861,0.03250034,0.000008708973,0.00001685894,0.0004951941,0.00004909575,0.001259017,0.9591277,0.0001409131,0.00627697,0.000008454858],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9720169,0.009042518,0.01245696,0.0002105596,0.00005336819,0.00003864373,0.0009042906,0.0001648088,0.005111828],"genre_scores_gemma":[0.9868564,0.003287816,0.005916413,0.0001002011,0.0000159513,0.00003438586,0.0005540959,0.00002203173,0.003212714],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001948969,"threshold_uncertainty_score":0.003875196,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03087736982291415,"score_gpt":0.3407480579665331,"score_spread":0.309870688143619,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}