{"id":"W2137095509","doi":"10.1534/genetics.114.172874","title":"Mitotic Accumulation of Dimethylated Lysine 79 of Histone H3 Is Important for Maintaining Genome Integrity During Mitosis in Human Cells","year":2014,"lang":"en","type":"article","venue":"Genetics","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Canadian Institutes of Health Research; Research Manitoba; Manitoba Health Research Council","keywords":"Biology; Mitosis; Histone; Cell biology; Histone H2B; Histone H3; Mitotic exit; Genetics; Ubiquitin; Ubiquitin ligase; Cell division; Cell; Spindle apparatus; DNA; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004377015,0.0001613197,0.000284589,0.0001314753,0.0000476479,0.000007201747,0.0001557118,0.0002133584,0.00001076969],"category_scores_gemma":[0.00009257261,0.0001754221,0.0001202004,0.0001448739,0.00006477565,0.00000275933,0.00007673944,0.00008580843,3.924463e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002907302,"about_ca_system_score_gemma":0.00003563212,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005139014,"about_ca_topic_score_gemma":0.00007367247,"domain_scores_codex":[0.9985649,0.00007295032,0.0006852013,0.0003104532,0.0001403108,0.00022617],"domain_scores_gemma":[0.9989747,0.00003210451,0.0003739792,0.0003768048,0.0001879539,0.00005448978],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004566072,0.00007007614,0.01794296,0.00007950771,0.00003374549,1.860322e-7,0.0001591329,0.003792159,0.9774032,0.00002387959,0.0000044279,0.0004450339],"study_design_scores_gemma":[0.0007791952,0.0003422021,0.04827042,0.00002299195,0.00004286592,3.058974e-7,0.00003445382,0.00237039,0.9470857,0.0004879228,0.0003945445,0.0001690019],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9888123,0.001186351,0.009525962,0.00002665844,0.00008353176,0.0002804317,0.0000352303,0.000004737542,0.00004483102],"genre_scores_gemma":[0.9921052,0.0002561612,0.007275207,0.00001488133,0.0001015338,0.00001076813,0.00015344,0.00003009091,0.000052663],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03032746,"threshold_uncertainty_score":0.7153504,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03087736982291415,"score_gpt":0.3407480579665331,"score_spread":0.309870688143619,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}